Publications by authors named "Carmen Loredana Petrea Cliveti"

The COVID-19 pandemic has introduced challenges in pediatric care, especially due to the emergence of Multisystem Inflammatory Syndrome in Children (MIS-C), a severe condition associated with SARS-CoV-2 infection. This study investigated the impact of hyponatremia and antidiuretic hormone (ADH) secretion corelated to clinical outcomes in these patients. We conducted a retrospective cohort study, including 118 pediatric patients, with a detailed sub-cohort analysis of 53 patients for ADH secretion markers.

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COVID-19-associated multisystem inflammatory syndrome in children (MIS-C) is a rare autoimmune disorder characterized by a range of polymorphic manifestations, similar to but distinct from other well-known inflammatory syndromes in children. We conducted a retrospective-descriptive study in which we summarized the clinical presentation of, biomarker variations in, and complications occurring in patients diagnosed with MIS-C, admitted to the Emergency Clinical Hospital for Children "Sf. Ioan", Galati, between July 2020 and June 2024.

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Article Synopsis
  • - Pediatric patients with polyuria polydipsia syndrome (PPS) can be hard to diagnose due to difficulties with the standard water deprivation test (WDT), but copeptin is a promising biomarker for better diagnosis.
  • - This study evaluates the effectiveness of baseline copeptin measurements and stimulation tests against WDT to differentiate between types of diabetes insipidus and primary polydipsia in children.
  • - Findings show high sensitivity (0.98) and specificity (0.947) for copeptin tests, indicating it could be a reliable and less invasive diagnostic alternative, calling for more standardized protocols in future research.
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Article Synopsis
  • * New autoimmune disorders, including multisystemic inflammatory syndrome in children (MIS-C) and systemic lupus erythematosus (SLE), have been reported after COVID-19.
  • * The article discusses a pediatric case of SLE that developed three and a half months after COVID-19, suggesting a potential link between SARS-CoV-2 and Epstein-Barr in triggering this condition.
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