Fluctuation of HCV viral load before seroconversion in a healthy volunteer blood donor.

Background: Newly implemented NAT has been shown to be able to effectively identify HCV-positive blood donated during the preseroconversion period.

Study Design And Methods: EDTA-plasma pools of 24 donations were tested using an HIV-1/HCV multiplex NAT under an FDA-approved IND application. Samples in a positive pool were retested individually.