Publications by authors named "Carmen Guaza Rodriguez"

Article Synopsis
  • Rutin is a flavonoid found in many fruits and plants that has shown anti-inflammatory and antioxidant benefits, but its mechanisms on microglia (immune cells in the brain) were not well understood.
  • In this study, rutin was tested on microglial cells both in their resting state and when stimulated with lipopolysaccharide (LPS), revealing that it promotes microglial proliferation and shifts their activation towards a protective M2 phenotype.
  • The treatment with rutin also decreased pro-inflammatory cytokines and increased the production of the anti-inflammatory cytokine IL10, suggesting its potential as a therapeutic option for neurodegenerative diseases.
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