Publications by authors named "Carmen Gonzalez-Azcona"
Unlabelled: Livestock-associated methicillin-resistant (LA-MRSA), such as clonal-complex (CC)398, are of clinical relevance due to their multi-drug resistance profiles, adding to the overall burden of MRSA in humans. The objective was to evaluate the double-zone hemolysis (DZH) test as a simple and reliable method for detecting LA-MRSA in the clinical microbiology laboratory. isolates assigned to CC398 ( = 183; 152 MRSA/31 methicillin-susceptible [MSSA]), CC1 ( = 44; MRSA), and other CCs ( = 144; 94 MRSA/50 MSSA) were investigated.
View Article and Find Full Text PDFWastewater treatment plants (WWTPs) are hotspots for the spread of antimicrobial resistance into the environment. This study aimed to estimate the proportion of clinically relevant antimicrobial-resistant bacteria in two Spanish urban WWTPs, located in the region of La Rioja (Spain); Methods: Ninety-four samples (48 water/46 sludge) were collected and streaked on ten different selective media, in order to recover the culturable bacterial diversity with relevant resistance phenotypes: Extended-Spectrum β-Lactamase-producing / (ESBL-Ec/Kp), Carbapenem-resistant (CR-E), Methicillin-resistant (MRSA), and Vancomycin-resistant / (VR-/). Isolates were identified by MALDI-TOF and were tested for antimicrobial susceptibility using the disk diffusion method.
View Article and Find Full Text PDFPurpose: Staphylococcus aureus is one of the most prevalent pathogens in cystic fibrosis (CF), being of special relevance those methicillin-resistant (MRSA). The livestock-associated (LA)-MRSA lineage CC398 is an emerging problem, specially related to pig-farming (PF) environments. The objective was to characterize the S.
View Article and Find Full Text PDFThe present study aimed to determine the phenotypic and genotypic characteristics of . isolates from the nasal swabs of goats. A total of 232 nasal samples (one per animal) were collected from goats on 13 farms located in two regions of Algeria and were analyzed for the presence of .
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated the transfer and antimicrobial resistance (AMR) of coagulase-negative staphylococci (CoNS) between healthy dogs and their owners, collecting nasal samples from 34 dogs and 41 people across 27 households.
- - A total of 216 CoNS isolates were identified, with varying predominant species and significant intra-species AMR diversity, revealing that many carriers displayed multidrug resistance and different AMR profiles.
- - The highest resistance was observed against erythromycin and mupirocin, and a linezolid-resistant isolate was also found, indicating health risks associated with AMR gene transfer between pets and humans.
Methicillin resistance, mediated by the gene in staphylococci and mammaliicocci, has caused tremendous setbacks in the use of antibiotics in human and veterinary medicine due to its high potential of presenting the multidrug resistance (MDR) phenotype. Three other analogs exist, of which the has evolutionary been associated with methicillin-resistant (MRSA) in wild animals, thus loosely referred to as the wild MRSA. In this study, we present an epidemiological review and genomic analysis of non- staphylococci and mammaliicocci that carry the -mediated methicillin resistance trait and determine whether this trait has any relevant link with the One Health niches.
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- A study examined 259 staphylococci from healthy nestling white storks, focusing on their antimicrobial activity against 14 target bacteria.
- Nine of these staphylococci were identified as antimicrobial-producing isolates, with varying levels of activity primarily against Gram-positive bacteria.
- Notably, one isolate (X3764) demonstrated significant antimicrobial effects against a broad range of representative bacterial species from the storks, and genetic analysis suggested the presence of antimicrobial compounds in these isolates.