Publications by authors named "Carmen Diaz Donado"
Article Synopsis
- Chronic spontaneous urticaria (CSU) is a skin disease with complicated causes, and serum amyloid A (SAA) might serve as a biomarker, but its role has not been thoroughly investigated.
- A study involving 67 CSU patients found that higher SAA-1 levels are linked to greater disease activity (measured by Urticaria Activity Score, UAS7) and poorer control of symptoms.
- The findings suggest that SAA-1 could be a useful marker for monitoring CSU severity, but more research is needed to assess its effectiveness in tracking other treatment outcomes.
Efficacy and Safety of Omalizumab (Xolair) for Cholinergic Urticaria in Patients Unresponsive to a Double Dose of Antihistamines: A Randomized Mixed Double-Blind and Open-Label Placebo-Controlled Clinical Trial.
J Allergy Clin Immunol Pract
August 2020
Background: Cholinergic urticaria (UCOL) is a highly disabling inducible urticaria triggered by an increase in core body temperature.
Objective: To explore the safety and efficacy of omalizumab in controlling UCOL.
Methods: We conducted a multicenter randomized mixed double-blind and open-label (first 4 months blinded followed by 8 months open-label) placebo-controlled clinical trial in 22 patients suffering from UCOL who were unresponsive to a double dose of antihistamines.
Intraoral contact allergy reactions are clinically poorly differentiated and understood, and are not very commonly described in the specialized literature. Although such reactions appear to be scantly relevant, evidence suggests that they may be more frequent than previously believed. No single or specific clinical picture of intraoral contact allergy exists, though lichenoid reactions appear to be the most common manifestations.
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