Publications by authors named "Carmen Castaneda"

This article presents the results of soil and water analysis plus the plans -or "maps"- from the Report [1] issued 1974 on salt-affected soils in a new irrigation district located in the semi-arid Bardenas area of Aragón, northern Spain (Fig. 1). The survey was carried out by the now defunct Institute for Agrarian Reform and Development (i.

View Article and Find Full Text PDF

Despite cognitive symptoms being very important in schizophrenia, not every schizophrenic patient has a significant cognitive deficit. The molecular mechanisms underlying the different degrees of cognitive functioning in schizophrenic patients are not sufficiently understood. We studied the relation between brain-derived neurotrophic factor (BDNF) and cognitive functioning in two groups of schizophrenic patients with different cognitive statuses.

View Article and Find Full Text PDF

Background: Psychosis is related to neurochemical changes in deep-brain nuclei, particularly suggesting dopamine dysfunctions. We used an magnetic resonance imaging-based technique called quantitative susceptibility mapping (QSM) to study these regions in psychosis. QSM quantifies magnetic susceptibility in the brain, which is associated with iron concentrations.

View Article and Find Full Text PDF

Microbial communities inhabiting hypersaline wetlands, well adapted to the environmental fluctuations due to flooding and desiccation events, play a key role in the biogeochemical cycles, ensuring ecosystem service. To better understand the ecosystem functioning, we studied soil microbial communities of Salineta wetland (NE Spain) in dry and wet seasons in three different landscape stations representing situations characteristic of ephemeral saline lakes: S1 soil usually submerged, S2 soil intermittently flooded, and S3 soil with halophytes. Microbial community composition was determined according to different redox layers by 16S rRNA gene barcoding.

View Article and Find Full Text PDF

Background And Hypothesis: Abnormal functional connectivity between brain regions is a consistent finding in schizophrenia, including functional magnetic resonance imaging (fMRI) studies. Recent studies have highlighted that connectivity changes in time in healthy subjects. We here examined the temporal changes in functional connectivity in patients with a first episode of psychosis (FEP).

View Article and Find Full Text PDF

Background: Educational attainment is associated with wellbeing and health, but patients with schizophrenia achieve lower levels of education than people without. Several effective interventions can ameliorate this situation. However, the magnitude of the education gap in schizophrenia and its change over time are unclear.

View Article and Find Full Text PDF

Our dataset contains the scans of 278 paper prints of contacts from a photogrammetric flight of 1972, plus a diagram for the relative location of each of the photograms. The paper prints served three years later, i.e.

View Article and Find Full Text PDF

Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project.

View Article and Find Full Text PDF

Introduction: Little is known about predictors of clinical response to clozapine treatment in treatment-resistant psychosis. Most published cohorts are small, providing inconsistent results. We aimed to identify baseline clinical predictors of future clinical response in patients who initiate clozapine treatment, mainly focusing on the effect of age, duration of illness, baseline clinical symptoms and homelessness.

View Article and Find Full Text PDF
Article Synopsis
  • The study examines cognitive performance in 1175 Latin American individuals, including 864 with schizophrenia and 311 controls, to understand the impact of socioeconomic status (SES) and clinical factors.
  • Patients with schizophrenia demonstrated poorer cognitive abilities than non-affected individuals across all measured domains, and their cognitive performance was significantly influenced by factors like education and income.
  • The research highlights that while patients did not exhibit accelerated cognitive aging, their cognitive abilities were more adversely affected by lower SES, emphasizing the impact of demographic and socioeconomic challenges in low- and middle-income countries.
View Article and Find Full Text PDF

The dataset presented comprises (raw data) scans of the marked paper contact prints from a dedicated photogrammetric flight and a diagram showing the location of each of these photograms. The flight was commissioned specifically for the soil survey presented herein. The scanned paper prints are those used in the field to characterize the soil salinity of 27,500 ha within the Flumen irrigation district, in the semi-arid Central Ebro Basin, in Spain.

View Article and Find Full Text PDF

Background: Cannabis use among young people in Chile has increased significantly in the last years. There is a consistent link between cannabis and psychosis.

Aim: To compare cannabis use in patients with a first episode of psychosis and healthy controls.

View Article and Find Full Text PDF

Background: Social and environmental factors such as poverty or violence modulate the risk and course of schizophrenia. However, how they affect the brain in patients with psychosis remains unclear.

Aims: We studied how environmental factors are related to brain structure in patients with schizophrenia and controls in Latin America, where these factors are large and unequally distributed.

View Article and Find Full Text PDF

Background: Evidence suggests the incidence of non-affective psychotic disorders (NAPDs) varies across persons and places, but data from the Global South is scarce. We aimed to estimate the treated incidence of NAPD in Chile, and variance by person, place and time.

Methods: We used national register data from Chile including all people, 10-65 years, with the first episode of NAPD (International Classification of Diseases, Tenth Revision: F20-F29) between 1 January 2005 and 29 August 2018.

View Article and Find Full Text PDF

The aim of the present study consists on the establishment of any relationship or interaction between geomorphological processes and vegetation/habitat distribution in an area with strong environmental gradients: an active saline lake in NE Spain. The resulting maps of the major geoforms and CORINE habitats within the lacustrine area were overlain to determine any significant relationships, taking into account the elevation derived from Lidar data. Whereas the geoforms resulted to have a roughly concentric distribution, the habitats appeared to be spread across different areas, and flooding frequency seemed not to be a determining factor in their altitudinal distribution.

View Article and Find Full Text PDF

Aim: Studies conducted in the United States have highlighted a higher prevalence of metabolic alterations (MA) in Latino population and Latino psychotic patients. Metabolic risk in psychosis is known to be present from initial stages of the disease. To better characterize this population, we explored the prevalence of MA and metabolic syndrome (MS) in early psychosis patients in a Latin American country.

View Article and Find Full Text PDF

Social and environmental factors are known risk factors and modulators of mental health disorders. We here conducted a nonsystematic review of the neuroimaging literature studying the effects of poverty, urbanicity, and community violence, highlighting the opportunities of studying non-Western developing societies such as those in Latin America. Social and environmental factors in these communities are widespread and have a large magnitude, as well as an unequal distribution, providing a good opportunity for their characterization.

View Article and Find Full Text PDF

Soil microbial communities (both Bacteria and Archaea) were studied after 16S rRNA genes massive sequencing in two hypersaline and gypsum-rich contrasted sites located in NE Spain. Soil microbial communities were also locally analysed according to environmental variables, including geological, physico-chemical, biogeochemically, and climatic data. Typical soil characteristics, climate data, and plant composition clearly split the two sites and major differences among the microbial communities for the areas were initially expected.

View Article and Find Full Text PDF

Unlabelled: The safety profile of lenalidomide use in lower-risk myelodysplastic syndromes (MDS) patients with del(5q) is well-established, but less is known in non-del(5q) patients. We provide safety data from a randomized, phase 3 trial evaluating lenalidomide in 239 patients with lower-risk non-del(5q) MDS ineligible/refractory to erythropoiesis-stimulating agents (ESAs). Compared with placebo, lenalidomide was associated with a higher incidence of grade 3-4 treatment-emergent adverse events (TEAEs; 86% vs.

View Article and Find Full Text PDF

Aim: To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort.

Methods: Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off point, and this was related to remission at 10 weeks of treatment.

View Article and Find Full Text PDF

Highly soluble salts are undesirable in agriculture because they reduce yields or the quality of most cash crops and can leak to surface or sub-surface waters. In some cases salinity can be associated with unique history, rarity, or special habitats protected by environmental laws. Yet in considering the measurement of soil salinity for long-term monitoring purposes, adequate methods are required.

View Article and Find Full Text PDF

The Monegros Desert contains one of the largest sets of inland saline lakes in Europe constituting a threatened landscape of great scientific and ecological value with large number of reported endemisms. We analyzed bacteria, archaea, and microbial eukaryotes from 11 saline lakes in winter and spring by rRNA gene fingerprinting and sequencing covering large salinity (2.7-22.

View Article and Find Full Text PDF