Is a Technetium-99m Macroaggregated Albumin Scan Essential in the Workup for Selective Internal Radiation Therapy with Yttrium-90? An Analysis of 532 Patients.

Purpose: To determine if baseline patient, tumor, and pretreatment evaluation characteristics could help identify patients who require technetium-99m (Tc) macroaggregated albumin (Tc MAA) imaging before selective internal radiation therapy (SIRT).

Materials And Methods: In this retrospective analysis, 532 consecutive patients with primary (n = 248) or metastatic (n = 284) liver tumors were evaluated between 2006 and 2015. Variables were compared between patients in whom Tc MAA imaging results contraindicated/modified SIRT administration with yttrium-90 (Y) resin microspheres and those who were treated as initially planned.