Publications by authors named "Carmen Arino-Palao"
Endocr Pathol
September 2024
Article Synopsis
- - Medullary thyroid carcinoma (MTC) is a rare cancer originating from the thyroid's neuroendocrine C-cells, and a new two-tier grading system based on tumor characteristics like proliferation and necrosis has been established to help predict patient outcomes.
- - A transcriptomic analysis of 21 MTC samples revealed a significant upregulation of various genes in high-grade tumors, suggesting distinct molecular pathways involved in tumor aggressiveness, such as DNA damage repair and apoptosis.
- - The study found that DLL3 expression is correlated with poorer survival rates in MTC patients, particularly when DLL3 is overexpressed in at least 50% of tumor cells, indicating its potential as a biomarker for aggressive disease. *
