Publications by authors named "Carmen Alcocer Cordellat"
In hospitalized children, SARS-CoV-2 infection can present as either a primary reason for admission (patients admitted for COVID-19) or an incidental finding during follow-up (patients admitted with COVID-19). We conducted a nested case-control study within a cohort of pediatric patients with confirmed SARS-CoV-2 infection, to investigate the concentration of plasma nucleocapsid antigen (N-Ag) in children admitted for COVID-19 or with COVID-19. While reverse transcriptase polymerase chain reaction Ct values in nasopharyngeal swab were similar between the two groups, children admitted for COVID-19 had a higher rate of detectable N-Ag (12/18 (60.
View Article and Find Full Text PDFBlood spotted onto filter paper can be easily collected outside healthcare facilities and shipped to a central laboratory for serological testing. However, dried blood testing generally requires manual processing for pre-analytical steps. In this study, we used a standardized blood collection device combined with an automated elution system to test illegal gold miners living in French Guiana for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis.
View Article and Find Full Text PDFArticle Synopsis
- SARS-CoV-2 nucleocapsid antigen (N-Ag) can be found in the urine of COVID-19 patients, indicating a potential indicator of disease severity.
- A study involving 82 patients showed high levels of urinary N-Ag during the first two weeks of infection, with significant correlations to severe clinical features, like ICU admission and abnormal blood markers.
- The findings suggest that urinary N-Ag could serve as a more accurate predictor of severe COVID-19 compared to plasma N-Ag, highlighting its possible use in clinical assessments.