Publications by authors named "Carmelo Garcia"

Millions of people use public transport systems daily, hence their interest for the epidemiology of respiratory infectious diseases, both from a scientific and a health control point of view. This article presents a methodology for obtaining epidemiological information on these types of diseases in the context of a public road transport system. This epidemiological information is based on an estimation of interactions with risk of infection between users of the public transport system.

View Article and Find Full Text PDF

This paper expands upon a previous publication and is the natural continuation of an earlier study which presented an industrial validator of expiration codes printed on aluminium or tin cans, called MONICOD. MONICOD is distinguished by its high operating speed, running at 200 frames per second and validating up to 35 cans per second. This paper adds further detail to this description by describing the final stage of the MONICOD industrial validator: the process of effectively validating the characters.

View Article and Find Full Text PDF

Indoor positioning systems (IPS) are used to locate people or objects in environments where the global positioning system (GPS) fails. The commitment to make bluetooth low energy (BLE) technology the leader in IPS and their applications is clear: Since 2009, the Bluetooth Special Interest Group (SIG) has released several improved versions. BLE offers many advantages for IPS, e.

View Article and Find Full Text PDF

In road-based mass transit systems, travel time is a key factor in providing quality of service. This article proposes a method of predicting travel time for this type of transport system. This method estimates travel time by taking into account its historical behaviour, represented by historical profiles, and the current behaviour recorded on the public transport vehicle for which the prediction is to be made.

View Article and Find Full Text PDF

The development of efficient mass transit systems that provide quality of service is a major challenge for modern societies. To meet this challenge, it is essential to understand user demand. This article proposes using new time-dependent attributes to represent demand, attributes that differ from those that have traditionally been used in the design and planning of this type of transit system.

View Article and Find Full Text PDF

Quality is an essential aspect of public transport. In the case of regular public passenger transport by road, punctuality and regularity are criteria used to assess quality of service. Calculating metrics related to these criteria continuously over time and comprehensively across the entire transport network requires the handling of large amounts of data.

View Article and Find Full Text PDF

This paper presents a study of positioning system that provides advanced information services based on Wi-Fi and Bluetooth Low Energy (BLE) technologies. It uses Wi-Fi for rough positioning and BLE for fine positioning. It is designed for use in public transportation system stations and terminals where the conditions are "hostile" or unfavourable due to signal noise produced by the continuous movement of passengers and buses, data collection conducted in the constant presence thereof, multipath fading, non-line of sight (NLOS) conditions, the fact that part of the wireless communication infrastructure has already been deployed and positioned in a way that may not be optimal for positioning purposes, variable humidity conditions, etc.

View Article and Find Full Text PDF

This paper presents an architecture model for the development of intelligent systems for public passenger transport by road. The main objective of our proposal is to provide a framework for the systematic development and deployment of telematics systems to improve various aspects of this type of transport, such as efficiency, accessibility and safety. The architecture model presented herein is based on international standards on intelligent transport system architectures, ubiquitous computing and service-oriented architecture for distributed systems.

View Article and Find Full Text PDF

In this article we describe a low-cost, minimally-intrusive system for the efficient management of parking spaces on both public roads and controlled zones. This system is based on wireless networks of photoelectric sensors that are deployed on the access roads into and out of these areas. The sensors detect the passage of vehicles on these roads and communicate this information to a data centre, thus making it possible to know the number of vehicles in the controlled zone and the occupancy levels in real-time.

View Article and Find Full Text PDF

Expiration date labels are ubiquitous in the food industry. With the passage of time, almost any food becomes unhealthy, even when well preserved. The expiration date is estimated based on the type and manufacture/packaging time of that particular food unit.

View Article and Find Full Text PDF

The development of public transit systems that are accessible and safe for everyone, including people with special needs, is an objective that is justified from the civic and economic points of view. Unfortunately, public transit services are conceived for people who do not have reduced physical or cognitive abilities. In this paper, we present an intelligent public transit system by highway with the goal of facilitating access and improving the safety of public transit for persons with special needs.

View Article and Find Full Text PDF

This study describes a system for the automatic recording of positioning data for public transport vehicles used on roads. With the data provided by this system, transportation-regulatory authorities can control, verify and improve the routes that vehicles use, while also providing new data to improve the representation of the transportation network and providing new services in the context of intelligent metropolitan areas. The system is executed autonomously in the vehicles, by recording their massive positioning data and transferring them to remote data banks for subsequent processing.

View Article and Find Full Text PDF

Unwanted photoinduced responses are well-known adverse effects of most promazine drugs, including levomepromazine (LPZ, Levoprome(®) or Nozinan(®)). This drug is indicated in psychiatry primarily for the treatment of schizophrenia and other schizoaffective disorders. Levomepromazine's particular sedative properties make it especially fit for use in psychiatric intensive care.

View Article and Find Full Text PDF

This paper presents OnRoute, a framework for developing and running ubiquitous software that provides information services to passengers of public transportation, including payment systems and on-route guidance services. To achieve a high level of interoperability, accessibility and context awareness, OnRoute uses the ubiquitous computing paradigm. To guarantee the quality of the software produced, the reliable software principles used in critical contexts, such as automotive systems, are also considered by the framework.

View Article and Find Full Text PDF

New spiroaminoborate esters derived from 1,1-diphenylprolinol, ephedrine and dihydroquinine with different alkoxy substituents were prepared as stable crystalline compounds and characterized by spectroscopical analysis and specific rotation. The structure of the spiroborate 4 derived from 1,1-diphenylprolinol and dicyclohexyl-1,1'-diol was confirmed by X-ray analysis.

View Article and Find Full Text PDF

2-chlorothioxanthone (CTX) is used as photoinitiator for the reticulation of synthetic resins and for the preparation of pharmaceuticals. It was previously determined that CTX is the primary photoproduct of z-chlorprothixene (CPTX) when irradiated at 313 nm and is formed in an autocatalyzed reaction through an energy-transfer mechanism (Piñero et al. [2009] Photochem.

View Article and Find Full Text PDF

Changes in the emission fluorescence intensity of pheophorbide-a (PHEO) in the presence of carboquone (CARBOQ) were used to obtain the association constant, the number of CARBOQ molecules interacting with PHEO, and the fluorescence quantum yield of the complex. Excitation spectra of mixtures of PHEO and CARBOQ in ethanol (EtOH) show an unresolved doublet in the red-most excitation band of PHEO, indicating the formation of a loose ground-state complex. The 1:1 CARBOQ-PHEO complex shows a higher fluorescence quantum yield in EtOH (0.

View Article and Find Full Text PDF

Quinones are one of the largest classes of antitumor agents approved for clinical use, and several antitumor quinones are in various stages of clinical and preclinical development. Many of these are metabolites of, or are, environmental toxins. Because of their chemical structure they are known to enhance electron transfer processes such as ascorbate oxidation and NO reduction.

View Article and Find Full Text PDF

The novel dimethoxyl(aminoalkoxy)borate 1 was isolated as a white crystalline dimer joined by H-bonding as evidenced by X-ray analysis, and demonstrated to be a highly effective catalyst for the asymmetric reduction of representative prochiral ketones with borane-DMS. Optically pure alcohols were obtained using only 1 mol% of catalyst 1 in up to 99% ee.

View Article and Find Full Text PDF

Chlorprothixene (CPTX, Taractan) is a low potency antipsychotic mainly used for the treatment of psychotic disorders (e.g. schizophrenia) and acute mania occurring as part of bipolar disorders.

View Article and Find Full Text PDF

Phenothiazines derivatives are versatile compounds that are used in many fields, depending on the type and position of the substitution on the parent molecule. The photochemical, photophysical and electrochemical properties of several phenothiazine derivatives have been previously reported in detail. However, no reports have been presented for 2-aminophenothiazine (APH), a candidate that provides for the further chemical modification and the introduction of specific substituents.

View Article and Find Full Text PDF

The mechanisms that trigger the phototoxic response to 2-chlorophenothiazine derivatives are still unknown. To better understand the relationship between the molecular structure of halogenated phenothiazines and their phototoxic activity, their photophysics and photochemistry were studied in several alcohols. The photodestruction quantum yields were determined under anaerobic conditions using monochromatic light (313 nm).

View Article and Find Full Text PDF

A novel cyclolignanic quinone, 7-acetyl-3',4'-didemethoxy-3',4'-dioxopodophyllotoxin (CLQ), inhibits topoisomerase II (TOPO II) activity. The extent of this inhibition was greater than that produced by the etoposide quinone (EQ) or etoposide. Glutathione (GSH) reduces EQ and CLQ to their corresponding semiquinones under anaerobic conditions.

View Article and Find Full Text PDF

Imipramine (IPA) and its derivatives are used widely for the treatment of depression and other mental disorders. Although there are more than 20 FDA-approved antidepressant drugs, the search continues for better compounds with fewer deleterious side effects and higher efficacy. Over the past decade, several classes of antipsychotic drugs have been developed, which-in spite of their structural diversity-share an ability to modulate neurotransmission and to produce undesirable side effects.

View Article and Find Full Text PDF

Introduction: The use of thoracic drains after cardiac surgery is distressing to patients and can cause a local inflammatory response. The objective of this study was to demonstrate the efficacy and safety of the flexible Blake drain for mediastinal and pleural drainage following cardiac surgery.

Material And Method: We retrospectively studied 292 consecutive patients who underwent open heart surgery.

View Article and Find Full Text PDF