Publications by authors named "Carmela Incognito"
Article Synopsis
- Venous thromboembolism (VTE) is a complex disease influenced by multiple factors, particularly inflammation, which can lead to a pro-thrombotic state.
- Anticoagulant medications, like low-molecular-weight heparins (LMWH) and direct oral anticoagulants (DOACs), are key treatments for VTE, with LMWH also lowering inflammatory markers like interleukin (IL)-6.
- A study found that DOACs reduced IL-6 levels in patients with deep vein thrombosis (DVT) compared to controls, suggesting that their anti-inflammatory effects may contribute to their treatment efficacy in VTE.
Statins (S) are widely used drugs for cardiovascular prevention however their utilization may cause a various grade of muscle toxicity. Sometime S discontinuation alone is not sufficient to revert muscle injury and this can evolve in serious inflammatory muscle disease. In this case immunosuppressive medications are required to achieve remission.
View Article and Find Full Text PDF