Publications by authors named "Carmel Sammut"
Article Synopsis
- Over 80 species in the commercially important genus are highlighted, with many being region-specific and crucial for understanding evolutionary history and ecology.
- Recent research with new Mediterranean specimens has revised the historical biogeography of morels, suggesting the Mediterranean basin as the likely origin instead of western North America.
- Detailed morphoanatomical analyses and new descriptions reveal stable features and propose a fresh evolutionary hypothesis for the genus.
Amitriptyline (AMI) has been in use for decades in treating depression and more recently for the management of neuropathic pain. A highly sensitive and specific LC-tandem mass spectrometry method was developed for simultaneous determination of AMI, its active metabolite nortriptyline (NOR) and their hydroxy-metabolites in human serum, using deuterated AMI and NOR as internal standards. The isobaric E-10-hydroxyamitriptyline (E-OH AMI), Z-10-hydroxyamitriptyline (Z-OH AMI), E-10-hydroxynortriptyline (E-OH NOR) and Z-10-hydroxynortriptyline (Z-OH NOR), together with their parent compounds, were separated on an ACE C column using a simple protein precipitation method, followed by dilution and analysis using positive electrospray ionisation with multiple reaction monitoring.
View Article and Find Full Text PDFA simple HPLC-UV method for the determination of ciprofloxacin in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
May 2015
A rapid and sensitive HPLC-UV method for the determination of ciprofloxacin in human plasma is described. Protein precipitation with acetonitrile was used to separate the drug from plasma protein. An ACE(®) 5 C18 column (250 mm×4.
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