Publications by authors named "Carmel Ryan"

Objective: Interventional pathologists have expanded their expertise by acquiring proficiency in ultrasound-guided thyroid fine-needle aspiration biopsy (FNAB) and are now required to optimize punction procedures due to low resources and digital workflows. The aim of this study is to compare FNAB sample adequacy in two series with one versus two slides available for cytopathological analysis and its influence on diagnosis categorization, time taken to reach a final diagnosis, scanning time and size of the digital files produced.

Methods: Patients were retrospectively selected based on the sampling of thyroid nodules using either two glass slides (two-slide group) or one slide only (one-slide group) and cytological diagnosis was performed using the second edition of the Bethesda system.

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Article Synopsis
  • Esophageal adenocarcinoma (EAC) is linked to visceral obesity and non-alcoholic fatty liver disease (NAFLD), but its prevalence and effects on EAC patients were previously unexplored.
  • A study involving 559 patients revealed that 42% had hepatic steatosis (HS), with HS related to visceral obesity, metabolic syndrome, and type 2 diabetes at higher rates compared to non-HS patients.
  • Despite the presence of HS and associated liver conditions, postoperative complications and long-term survival rates (53% for HS vs. 50% for non-HS) were similar, indicating NAFLD has little impact on surgical outcomes for EAC.
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A 44-year-old female presented with a two-month history of a neck mass, sore throat, hoarseness, and intermittent dysphagia. Examination revealed a "woody" hard swelling arising from the right lobe of the thyroid. Clinically this was felt to be classical Riedel's thyroiditis (RT).

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Importance: The follicular variant (FV) of papillary thyroid carcinoma (PTC) is an important subtype that can be difficult to diagnose using preoperative cytologic analysis.

Objective: To compare conventional and FV PTC with regard to preoperative cytologic diagnosis using a tiered thyroid cytologic reporting system, tumor size at diagnosis, presence of invasion, and implications on prognostic scores.

Design, Setting, And Participants: This retrospective study was conducted in an academic teaching hospital and included 99 patients with conventional (n = 65) or FV (n = 34) PTC.

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