Controlled cycles in spontaneous-timed noninvasive ventilation: Incidence and associated factors.

Background: The most-used ventilation mode in home mechanical ventilation (HMV) is spontaneous-timed, designed to be essentially spontaneous with a programmed backup rate.

Research Question: We do not know the real frequency of activation of controlled cycles, nor its associated factors.

Study Design: and Methods: We conducted a single-center cohort study of patients with chronic hypoventilation who were started on HMV.

Ambulatory adaptation to noninvasive ventilation in restrictive pulmonary disease: a randomized trial with cost assessment.

Background: Home mechanical ventilation is usually initiated in hospital. However, cost-effectiveness of inpatient set up has never been compared to outpatient adaptation in a randomized design. A Prospective, multicenter, non-inferiority trial was conducted comparing the effectiveness of adaptation to noninvasive mechanical ventilation (NIMV) performed in the ambulatory or hospital setting in patients with chronic respiratory failure secondary to restrictive thoracic disease, obesity-hypoventilation syndrome or neuromuscular disease.

[Pulmonary calcifications and chronic kidney failure].

Pulmonary calcification is relatively uncommon and typically asymptomatic. A number of diseases are associated with this disorder, including chronic kidney failure, infections, and lung amyloidosis. There are, moreover, a number of conditions, such as hypercalcemia, hyperphosphatemia, alkalosis, and alveolar damage, which predispose a patient to calcification.