Publications by authors named "Carlson M"

Background: A lateral extra-articular tenodesis (LET) is increasingly being utilized to augment an anterior cruciate ligament reconstruction because it has been shown to reduce the risk of postreconstruction graft failure or recurrent rotatory instability. Various femoral fixation techniques are available, including the use of an interference screw, staple, or suture anchor.

Purpose: To determine and compare the biomechanical properties of an LET graft when using an interference screw, staple, or suture anchor for the femoral fixation for a modified Lemaire LET.

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Purpose: To compare the performance of the photon-counting detector (PCD)-CT versus a state-of-the-art energy-integrating detector (EID)-CT to identify segments of the inferior tympanic canaliculus (Jacobsons nerve) and the mastoid canaliculus (Arnolds nerve).

Materials & Methods: Patients were prospectively recruited to undergo temporal bone CT on both EID-CT (Siemens Somatom Force) and PCD-CT (Siemens NAEOTOM Alpha) scanners under an IRB-approved protocol. Three neuroradiologists reviewed cases by consensus comparing the ability to identify the proximal, mid, and distal segments of the inferior tympanic canaliculus/Jacobsons nerve and mastoid canaliculus/Arnolds nerve on each scanner using 5-point Likert scales (with 1 indicating EID is far superior to PCD, 3 indicating they are equivalent, and 5 indicating PCD is far superior to EID).

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Background And Objectives: The intraosseous subarcuate loop (SL) is a unique variant of the anterior inferior cerebellar artery (AICA), where a loop of the artery is trapped in the petrous bone's subarcuate fossa (SF). Recognizing this variant is crucial for planning cerebellopontine angle (CPA) surgeries; however, data regarding its frequency and management vary in the published literature. A cohort from a single center was studied using MRI to assess its prevalence, and the findings were compared with the existing literature.

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Objective: To determine which ear environment risk factors impact ossiculoplasty hearing outcomes and to generate a statistically-valid grading system for ossiculoplasty outcome reporting.

Study Type: Retrospective case series.

Methods: A multi-institutional database was generated from cases performed between 2011 and 2019.

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Psoriasis is a chronic skin disease occasionally associated with abdominal symptoms and IBD. We aimed to characterize intestinal immune cells and the integrity of the intestinal barrier in psoriasis. Biopsies from the duodenum and colon were analyzed by flow cytometry and immunohistochemistry for the presence and activation status of different immune cell populations.

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Objective: To compare the utility of intraoperative electrically evoked auditory brainstem response (eABR) and electrically evoked stapedial reflex testing (eSRT) for cochlear nerve integrity monitoring during simultaneous translabyrinthine resection of vestibular schwannoma (VS) and cochlear implantation.

Study Design: Historical cohort study.

Setting: Tertiary academic referral center.

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Objective: To evaluate cochlear implant speech perception among patients with sporadic inner ear schwannoma who underwent ipsilateral implantation.

Study Design: Retrospective multi-institutional cohort study.

Setting: Eleven tertiary academic medical centers across Germany, Denmark, and the United States.

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Background And Purpose: 2D linear measurements are often used in routine clinical practice during vestibular schwannoma (VS) follow-up, primarily due to wider availability and ease of use. We sought to determine radiologist performance compared to 3D-volumetry, along with the impact of number of linear measurements, slice thickness and tumor volumes on these parameters.

Materials And Methods: Single center retrospective study with 97 patients (592 MRI studies).

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Background: High rates of psychological distress are present in veterinary healthcare professionals and elevated mental health stigma in the field may underlie psychological treatment reluctance. A psychoeducational programme designed to reduce distress associated with difficult veterinary client behaviours (i.e.

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Quadriceps weakness after anterior cruciate ligament reconstruction (ACLR) is a well-known phenomenon, with more persistent quadriceps weakness observed after ACLR with a bone-patellar tendon-bone or quadriceps tendon autograft than with a hamstring tendon autograft. Longstanding quadriceps weakness after ACLR has been associated with suboptimal postoperative outcomes and the progression of radiographic knee osteoarthritis, making the recovery of quadriceps size and strength a key component of ACLR rehabilitation. However, few articles have been written for the specific purpose of optimizing quadriceps size and strength after ACLR.

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Objective: To analyze cases of medial migration of vestibular schwannomas to propose an underlying mechanism.

Study Design: Retrospective chart review.

Patients: Ten patients from one institution with sporadic vestibular schwannomas that demonstrated medial migration toward the cerebellopontine angle on serial imaging were reviewed.

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Article Synopsis
  • The study aimed to find protein signatures in blood that could help identify individuals at high risk for inflammatory bowel disease (IBD), specifically Crohn's disease (CD) and ulcerative colitis.
  • Researchers analyzed blood samples from a large population, utilizing machine-learning methods to identify and validate these protein signatures across multiple cohorts.
  • A specific combination of 29 proteins was effective in differentiating preclinical CD cases from controls, achieving a high accuracy, while the prediction for ulcerative colitis was less robust but still significant.
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  • Olfactory dysfunction may signal early stages of Alzheimer's disease (AD), prompting research into the piriform cortex using tau PET-MR imaging.
  • A study of 94 older adults revealed increased tau uptake in the piriform cortex correlating with disease severity, particularly in those with Alzheimer’s compared to amyloid-negative controls.
  • The results indicate heightened tau levels in AD and mild cognitive impairment, connecting greater piriform uptake with poorer memory performance, while no significant changes were observed in cognitively unimpaired Parkinson's disease.
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Objective: To evaluate audiological outcomes of transcutaneous devices among individuals with mixed hearing loss (MHL) who underwent implantation with the Cochlear™ Osia® and Med-El Bonebridge™ devices.

Methods: Adults with MHL in at least one ear, including a best bone conduction (BBC) threshold of 30 dB HL or poorer, and air-bone gaps of 15 dB HL or more at one or more frequencies were implanted with the Cochlear™ Osia® or Med-El Bonebridge™ devices for MHL. Four-frequency pure tone average (PTA) was calculated for aided thresholds and compared to preoperative PTAs for BBC thresholds.

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Chronic recurrent multifocal osteomyelitis (CRMO) is a rare but underdiagnosed, severe inflammatory bone disease that primarily affects children. It's typically characterized by bone pain, especially within the metaphysis of long bones, clavicles, and vertebrae, but it can present in any bone and with varied presentation, including extraosseous symptoms that may be associated with other autoimmune/inflammatory diseases. Chronic recurrent multifocal osteomyelitis is a sterile bone disease that does not typically have an infectious source.

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  • Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that may be linked to cancer, prompting a study to explore this association.
  • A cohort study in Sweden analyzed 1,580 EoE patients and matched them with 7,533 reference individuals, tracking cancer development over a median of 7 years.
  • While no overall cancer risk was found in EoE patients, there was a significant increase in the risk of esophageal cancer and Barrett's esophagus, though these cases were very rare, warranting caution in interpreting the results.
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Introduction: Neighborhood environments may promote neurocognitive health in part by providing amenities that encourage physical activity. We examined associations between quantity of walkable facilities, including specifically physical activity facilities (e.g.

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Background: Brain cancer is a devastating and incurable disease that places a high burden of care on next of kin (NOK). NOK can play a core role in supporting end-of-life planning, including the decision to donate one's brain after death. Postmortem brain donation is crucial to research.

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Objective: The objective of this study was to explore the experiences of distressed people calling helplines regarding offer and uptake of financial services after cancer diagnosis.

Methods: Cancer patients and caregivers reported whether they had discussed then used financial services and perceptions surrounding service uptake. Associations between being offered services and demographic, clinical and financial characteristics were explored.

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Article Synopsis
  • The study aims to evaluate how different cochlear dose parameters affect hearing outcomes in patients with sporadic vestibular schwannoma (VS) who have serviceable hearing after undergoing stereotactic radiosurgery (SRS).
  • A total of 205 patients were analyzed over a period from 2007 to 2022, revealing that 62% of patients maintained serviceable hearing at 2 years, while this dropped to 15% by 10 years post-treatment.
  • Results showed a significant association between increased minimum cochlear dose and faster decline in hearing, indicating that this dose parameter should be a key consideration in planning radiosurgery for VS patients.
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Background And Purpose: Ultra-high-resolution (UHR) photon-counting-detector (PCD) CT improves image resolution but increases noise, necessitating use of smoother reconstruction kernels that reduce resolution below the system's 0.110 mm maximum spatial resolution. To address this, a denoising convolutional neural network (CNN) was developed to reduce noise in images reconstructed with the available sharpest reconstruction kernel while preserving resolution for enhanced temporal bone visualization.

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Background: Fluoropyrimidine (FP) chemotherapies are commonly prescribed for upper and lower gastrointestinal, breast and head and neck malignancies. Over 16,000 people with cancer require FP chemotherapies per annum in Australia. Between 10 and 40% patients experience grade 3-4 (≥ G3) toxicities that require hospital-based management ± intensive care admission.

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Article Synopsis
  • - This study compares cochlear implant (CI) outcomes for speech perception in patients with sporadic vestibular schwannoma (VS) treated through observation, radiosurgery, or microsurgery.
  • - Of the 100 patients analyzed, those who underwent microsurgery had poorer speech perception scores compared to those who were observed or treated with radiosurgery, with only 61% achieving open-set speech perception after microsurgery.
  • - The findings suggest that cochlear implants can be beneficial for sporadic VS patients, particularly those managed by observation or radiosurgery, as these groups showed significantly better outcomes in achieving open-set speech perception.
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Objective: To report the feasibility and potential utility of monitoring acoustic hearing on awake patients using intraoperative behavioral responses to threshold and suprathreshold stimuli while undergoing cochlear implantation (CI) under local anesthesia, without any form of sedation.

Study Design: Retrospective review of the first five cases performed by one surgeon.

Setting: Tertiary care academic medical center.

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