Infant lung function and maternal physical activity in the first half of pregnancy.

Background And Aim: Physical activity (PA) in pregnancy is important for maternal and possibly offspring health. To study the early origins of lung function we aimed to determine whether PA in the first half of pregnancy is associated with lung function in healthy 3-month-old infants.

Methods: From the general population-based Preventing Atopic Dermatitis and Allergies in Children birth cohort recruiting infants antenatally in Norway and Sweden, all 812 infants (48.

Physical activity in pregnancy: a Norwegian-Swedish mother-child birth cohort study.

Background: Physical activity during pregnancy is important for maternal and offspring health. Optimal conditions during pregnancy may help reduce the burden of noncommunicable diseases. National and international guidelines recommend at least 150 minutes of physical activity of at least moderate intensity per week.

Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial.

Background: Skin emollients applied during early infancy could prevent atopic dermatitis, and early complementary food introduction might reduce food allergy in high-risk infants. The study aimed to determine if either regular skin emollients applied from 2 weeks of age, or early complementary feeding introduced between 12 and 16 weeks of age, reduced development of atopic dermatitis by age 12 months in the general infant population.

Methods: This population-based 2×2 factorial, randomised clinical trial was done at Oslo University Hospital and Østfold Hospital Trust, Oslo, Norway; and Karolinska University Hospital, Stockholm, Sweden.

International Scientific Committee of Radionuclides in Nephrourology (ISCORN) consensus on renal transit time measurements.

This report is the conclusion of the international consensus committee on renal transit time (subcommittee of the International Scientific Committee of Radionuclides in Nephrourology) and provides recommendations on measurement, normal values, and analysis of clinical utility. Transit time is the time that a tracer remains within the kidney or within a part of the kidney (eg, parenchymal transit time). It can be obtained from a dynamic renogram and a vascular input acquired in standardized conditions by a deconvolution process.

The gamma camera as an absolute measurement device: determination of glomerular filtration rate in 99mTc-DTPA renography using a dual head gamma camera.

Aim: The aim of this study was to design a general nuclear medicine method for fast, accurate and direct determination of the clearance of a radioactive indicator provided that all uptake compartments of the radioactive indicator could be included in the field of view of the gamma camera.

Methods: The data material for clearance calculation in the gamma camera method (GCM) comprises: (1) a transmission map of a part of the body using a water filled flood field phantom with a uniform distribution of the radioisotope, (2) the background corrected activity curves in the anterior and posterior views over all uptake compartments following the injection of the radioactive indicator, and (3) the activity of the radioactive indicator in at least two blood samples drawn during the examination. With a view to determining glomerular filtration rate (GFR) in 99mTc-DTPA renography the gamma camera method was tested in a group of 26 adult subjects in whom GFR was determined simultaneously using the simplified multiple samples method (MSM) with plasma samples drawn 3-5 h following the injection of 51Cr-EDTA.

Radix mesiolingualis and radix distolingualis in a collection of permanent maxillary molars.

Two lingual root structures are occasionally found on human permanent maxillary molars. One of these is the normal lingual root, which is always present, the other is a supernumerary structure which can be located either mesiolingually (radix mesiolingualis (RML)) or distolingually (radix distolingualis (RDL)). The available literature refers only to the existence and location of RML and RDL Very small materials have, quite simply, hitherto precluded a more detailed description of these roots.

Direct deconvolution algorithms based on Laplace transforms in nuclear medicine applications.

A set of algorithms is presented for direct deconvolution of the residue signal of an organ with the input signal to the organ. The deconvolution process yields the residual impulse response from which the distribution of transit times and the important mean transit time can be readily determined. The deconvolution method is based on the Laplace transform and it requires that the input signal can be fitted with an expression consisting of one, two or three exponentials with or without a bolus term at zero time or a constant term.

Radix paramolaris and radix distomolaris in Danish permanent maxillary molars.

The School of Dentistry in Copenhagen possesses a collection of 96 human permanent maxillary molars (M sup) with a root complex, the macromorphology of which includes a facially located supernumerary root known as radix paramolaris (RP) and/or a distally located supernumerary root called radix distomolaris (RD). Systematic analysis of these teeth enabled the authors to establish precise criteria for the identification of RP and RD on M sup; 91.5% out of a total of 70 RP identified occurred on M3 sup, 7.

External and internal macromorphology in 3D-reconstructed maxillary molars using computerized X-ray microtomography.

Aim: The aim of this study was to perform a qualitative analysis of the relationship between the external and internal macromorphology of the root complex and to use fractal dimension analysis to determine the correlation between the shape of the outer surface of the root and the shape of the root canal.

Methodology: On the basis of X-ray computed transaxial microtomography, a qualitative and quantitative analysis of the external and internal macromorphology of the root complex in permanent maxillary molars was performed using well-defined macromorphological variables and fractal dimension analysis. Five maxillary molars were placed between a microfocus X-ray tube with a focal spot size of 0.

Root canals in two-rooted maxillary second molars.

The aim of this study was to register the root canal number, root canal position, and root canal cross-section in human two-rooted, permanent maxillary second molars. One hundred and fifty-nine such teeth extracted in Denmark were cross-sectioned at the mid-root level and apically in accordance with precise guidelines. The observations were made in a stereomicroscope, corresponding to the above-mentioned section levels.

The Ekman-Westborg-Julin syndrome: report of case.

The Ekman-Westborg-Julin Syndrome is reveiwed and a new case reported.

Uptake index and stimulated salivary gland response in 99Tcm-pertechnetate salivary gland scintigraphy in normal subjects.

With a view to improve the diagnosis of salivary gland diseases (in particular, Sjögrén's syndrome) associated with decreased salivary gland function and decreased stimulated salivary gland response, the normal range of radionuclide uptake function and the stimulated salivary gland response were established in 27 subjects without any known salivary gland disease. Following injection of 99Tcm-pertechnetate, sequential images were recorded for 40 min with oral administration of citric acid at 30 min. The total uptake index (TUI) was calculated as the sum of the background corrected count rates over the parotid and submandibular glands at 3 min divided by the injected dose.

Mandibular premolar differentiation.

The authors present a method for differentiating between human mandibular premolars: P1 inf and P2 inf. The material with which the method was developed consisted of 260 stone casts. On these, both premolars were present and were intact on at least one side.

Root canals in one-rooted maxillary second molars.

The Royal Dental College, Copenhagen, houses an extensive collection of human teeth extracted in Denmark. The collection currently contains 104 one-rooted, permanent maxillary second molars. The root complex on these teeth was sectioned at the junction between the coronal and the apical halves, i.

Morphometric analysis of occlusal groove-fossa-system in mandibular third molar.

Based on serially cut 200-microns-thick sections from 21 human mandibular third molars, a quantitative characterization was made of the morphology in the mesial and distal interlobal groove. Two parameters were used: depth of interlobal groove and structure angle. The interlobal groove depth varied between 0.

Radix paramolaris in permanent mandibular molars: identification and morphology.

The Royal Dental College, Copenhagen, houses an extensive collection of human teeth which have been extracted in Denmark. The collection presently includes 203 permanent mandibular molars with a root complex containing a facially-located supernumerary root. This macrostructure is named radix paramolaris (RP).

Radix entomolaris: identification and morphology.

The Royal Dental College, Copenhagen, houses an extensive collection of human teeth, extracted in Denmark. At present, the collection includes 398 permanent mandibular molars with a root complex containing a lingually-located supernumerary root. This macrostructure is called radix entomolaris (RE).

Root complex and root canal system: a correlation analysis using one-rooted mandibular second molars.

The principal aim of this investigation was to verify an expected, probable correlation between certain variables, which are initially represented in the macrostructure of the root complex corresponding to the cemento-dentin junction, and certain variables that subsequently manifest themselves in the root canal system. A material consisting of 76 one-rooted, permanent mandibular second molars (M2 inf) was used. The specimens were cut at the mid-root level and all observations were made on the coronal root segment using a stereomicroscope.

A method for determination of normal or abnormal blood volume in patients subjected to radionuclide cardiography.

The blood volume can be measured after labelling of red blood cells with technetium-99m. In addition, the blood volume and its standard error of estimate can be calculated from the subject's sex, height and deviation from desired weight. By comparing the measured blood volume with the estimated normal blood volume and using a statistical test, it can be decided whether a measured blood volume is normal or not.

A new method for determination of the rate constant for clearance of radioactive indicators in gamma camera hepatography. Clinical examples with 99mTc-diethyl-IDA and 99mTc-diethyl-iodo-IDA.

Application of Stewart-Hamilton's formula to the activity-time curve recorded over a left ventricular region of interest following an intravenous bolus injection of a radioactive indicator in gamma camera hepatography has resulted in a new method for determination of the clearance rate constant of the indicator (i.e. the ratio of the clearance to the plasma volume).

A new, simple and precise method for the determination of right ventricule forward ejection fraction in first-pass radionuclide cardiography.

A new method is presented for the determination of right ventricular ejection fraction (RVEF) in first-pass radionuclide cardiography. The method is simple to apply and it provides RVEF values with an experimental standard deviation of 3.4% over the whole range of right ventricular ejection fractions.

Glomerular filtration rate in adults estimated from 123iodine-hippuran and 99mtechnetium-diethylenetriaminepenta-acetic acid gamma camera renography.

In a retrospective study a close relationship was found between the rate constant for renal clearance of the radioactive indicator (lambda pk) and the glomerular filtration rate (GFR) measured by 51Cr-EDTA plasma clearance. The material comprised eighteen adult subjects submitted to 123I-hippuran gamma camera renography (IHGR) and twenty-two adult subjects to 99mTc-DTPA gamma camera renography (TDGR). The rate constant was calculated from a bi-exponential decomposition of the activity-time curve recorded within a small region of interest over the left ventricle.

Absorbed radiation dose in adults from iodine-131 and iodine-123 orthoiodohippurate and technetium-99m DTPA renography.

A mathematic model for evaluation of absorbed dose in radionuclide renography has been developed and programmed for automatic calculation in the computer. Input data to the model are readily available from the results of the renography and, hence, the method described is suitable for individual dose determinations in adults. Apart from the situation with very considerable outflow obstructions [131I]OIH single probe renography involves a 15-20 times smaller dose to radiation sensitive organs than [123I]OIH gamma camera renography.

Evaluation of forward stroke volume in first-pass radionuclide cardiography.

First-pass radionuclide cardiography and Zierler's area-over-height formula have been applied for determination of stroke volume. The method has three new features: (a) the region of interest comprises the entire cardiopulmonary circulation; (b) a prediction of (normal) blood volume based on deviation from desired weight; and (c) a correction of stroke volume in case of incomplete bolus injection. The method was verified in a pathological situation by an independent geometric method in equilibrium gated radionuclide cardiography.

Evaluation of regional cerebral circulation based on absolute mean transit times in radionuclide cerebral angiography.

In radionuclide cerebral angiography (RCA) the analysis of the activity-time curves recorded over the hemispheres following an intravenous bolus injection of a radioactive indicator permits the evaluation of absolute cerebral mean transit times (MTTcb). The inverse of MTTcb is an index of cerebral blood flow. The bolus parts of the cerebral activity curves were fitted with gamma-variate functions.