Publications by authors named "Carlos Valdespino"
Background: Acute rejection and graft function have not been completely clarified in early-steroid-withdrawal (ESW) patients. The objective of this study was to compare the effect of early steroid withdrawal on GFR, graft survival/rejection in recipients in a cohort treated with tacrolimus/mycophenolate mofetil compared to a control cohort.
Material And Method: Retrospective cohort, in 60 low immunological risk recipients between December 2005 and July 2010.
Article Synopsis
- Renal graft rupture (RGR) is a serious complication in kidney transplants, often linked to rejection and acute tubular necrosis.
- Traditional repair methods include sutures and various absorbable materials, but this report introduces the use of non-absorbable polypropylene mesh for repair, which hadn't been documented before.
- The case study shows that after using the polypropylene mesh on a cadaveric kidney transplant, the patient remained asymptomatic and had normal kidney function six months post-surgery, suggesting this method could be a cost-effective treatment option.
A total of 1,356 kidney transplants has been performed in the Hospital de Especialidades del Centro Médico Nacional de Occidente, IMSS, in Guadalajara Mexico, including 935 in the past 8 years. This represents an important increase of this activity in our country. Of the total transplants, 1,218 (90%) were from living donors and only 138 (10%) were from cadaveric donors, a number that we hope to increase.
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- The study investigates the risk factors for renal graft loss in Mexico and Latin America, focusing on patients who received their first kidney transplants between 1976 and 1999.
- A total of 326 patients were analyzed, with key findings indicating that acute rejection episodes and lower HLA haplotype matching significantly predicted graft loss.
- Overall, while graft survival rates were similar to those in developed countries, the main risks identified for long-term failure were acute rejection and HLA mismatching.