Cocaine is a commonly abused drug among people living with HIV, negatively affecting their health by slowing down the decline of viral production after starting antiretroviral therapy and leading to higher viral loads and faster disease progression.
The study focused on 434 women with varying ancestry participating in a national cohort study, analyzing the impact of cocaine use on the HIV latent reservoir in their CD4+ T-cells.
Results showed that current and prior cocaine users have significantly larger HIV latent reservoir sizes compared to non-users, highlighting the need for more research on cocaine's effects on women's HIV outcomes.