"Never sacrifice anything to laboratory work": The "physiological psychology" of Charles Richet (1875-1905).

Whilst best known as a Nobel laureate physiologist, Charles Robert Richet (1850-1935) was also a pioneer of scientific psychology. Starting in 1875 Richet had a leading role in the habilitation of hypnosis, in the institutionalization of psychology in France, and in the introduction of methodological innovations. Authoring several psychology books, Richet's works contributed to the recognition of the scientific nature of the discipline.

Camille Flammarion on the powers of the soul; Carlos S.

There is a long conceptual tradition that interprets phenomena such as clairvoyance and apparitions as evidence for a spiritual component in human beings. Examples of this appear in the literatures of mesmerism, Spiritualism and psychical research. The purpose of this Classic Text is to present excerpts from a book by French astronomer Camille Flammarion touching on this perspective.

Jules Bernard Luys on magnetic pathology.

In the mesmeric movement, one of the phenomena cited to defend the existence of magnetic and nervous forces was the visual perception of them in the form of luminous emanations from people, or effluvia. This Classic Text is an 1892 article by French neurologist, Jules Bernard Luys (1828-97), about the observation of such effluvia by hypnotized individuals. Interestingly, the luminous phenomena perceived from mentally diseased individuals and from healthy ones had particular properties.

Final chapter, From India to the Planet Mars: A Study of a Case of Somnambulism with Glossolalia, by Théodore Flournoy (1900).

Among the many attempts to explain mediumship psychologically at the turn of the century were the efforts of Swiss psychologist Théodore Flournoy (1854-1920). In his well-known book Des Indes à la Planète Mars (1900), translated as From India to the Planet Mars (1900), Flournoy analysed the mediumistic productions of medium Hélène Smith (1861-1929), consisting of accounts of previous lives in France and in India, and material about planet Mars. Flournoy explained the phenomena as a function of cryptomnesia, suggestive influences, and subconscious creativity, analyses that influenced both psychology and psychical research.

Cesare Lombroso on mediumship and pathology.

During the nineteenth century and the first decade of the twentieth, students of pathology such as Cesare Lombroso (1835-1909), the author of the excerpt presented here, became involved in observing, investigating and theorizing about the phenomena of Spiritualism, and mediumship in particular. The Classic Text presented here consists of an excerpt from Lombroso's writings which focus on the Italian medium Eusapia Palladino (1854-1918), who greatly influenced Lombroso's beliefs. Lombroso illustrates neglected theoretical ideas combining the interaction of pathology and what seem to be real psychic phenomena that have not received much attention in historical studies.

Joseph Maxwell on mediumistic personifications.

The study of mediumship received much impetus from the work of psychical researchers. This included ideas about the phenomena of personation, or changes in attitudes, dispositions and behaviours shown by some mediums that supposedly indicated discarnate action. The aim of this Classic Text is to reprint passages about this topic from the writings of French psychical researcher Joseph Maxwell (1858-1938), which were part of the contributions of some psychical researchers to reconceptualize the manifestations in psychological terms.

'Report of the Committee on Mediumistic Phenomena', by William James (1886): With an introduction by.

Mediumship was a topic of great interest to some nineteenth-century students of mental phenomena. Together with the phenomena of hypnosis and other manifestations, mediumship was seen by many as a dissociative phenomenon. The purpose of this Classic Text is to present an excerpt of an article about the topic that William James (1842-1910) published in 1886 in the Proceedings of the American Society for Psychical Research about American medium Leonora E.

'Visions of the Dying', by James H Hyslop (1907): With an introduction by.

Deathbed visions have been of interest to psychical researchers and others since the nineteenth century. This Classic Text presents a reprint of an article on 'Visions of the Dying' published in 1907 in the Journal of the American Society for Psychical Research by philosopher and psychical researcher James H. Hyslop (1854-1920).

Spiritist delusions and spiritism in the nosography of French psychiatry (1850-1950).

At the turn of the twentieth century there was a wave of delusions which had a direct link to spiritism in their form and content. These so-called spiritist or mediumistic delusions were the object of detailed study, and clinicians assigned them a place in nosography, especially in France. This work of classification was carried out as a function of the convictions and paradoxes that these delusions aroused; it also made it possible to question the relationship between pathology and belief.

Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations.

Introduction: Subcutaneous panniculitis-like T-cell lymphoma (SPTL-AB) and cutaneous gamma/delta T-cell lymphoma (CGD-TCL) are rare T-cell lymphomas with varying clinical courses. There is no standard treatment, although chemotherapy and hematopoietic stem cell transplantation are commonly used. We describe results using bexarotene for children and adults with these disorders.

Expression and functional role of inhibitor-of-apoptosis protein livin (BIRC7) in neuroblastoma.

We evaluated the expression of the inhibitor-of-apoptosis protein (IAP)livin (BIRC7)in 59 cases ofneuroblastoma (NBL) by quantitative RT-PCR. We also examined the role of livin in protecting tumor cells from chemotherapy drugs. Livin expression varied significantly amongtumors.

Late 19th- and early 20th-century discussions of animal magnetism.

The mesmerists explained the phenomena of what was later called hypnosis as the effects of a force called animal magnetism. Both psychologists' and physicians' writings generally create the impression that the magnetic movement disappeared after the mid-19th century. While the concept of animal magnetism declined significantly by the end of the 19th century, it did not disappear completely.

Out-of-body experiences and physical body activity and posture: responses from a survey conducted in Scotland.

Although there have been studies of some factors related to the features of out-of-body experiences (OBEs), the effect of physical body posture and activity has not been systematically explored. Over the years research has suggested that OBEs are more frequent in states of low physical activity and when the body is supine, in agreement with other findings related to alterations in consciousness. Thus, we predicted that OBEs would be associated with lying down and little or no physical activity, and that these factors would show a higher number of OBE features than OBEs in which the person was physically active and/or standing.

PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells.

Background: c-Met is a tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF), and both c-Met and its ligand are expressed in a variety of tissues. C-Met/HGF/SF signaling is essential for normal embryogenesis, organogenesis, and tissue regeneration. Abnormal c-Met/HGF/SF signaling has been demonstrated in different tumors and linked to aggressive and metastatic tumor phenotypes.

Ambroise August Liébeault and psychic phenomena.

Some nineteenth-century hypnosis researchers did not limit their interest to the study of the conventional psychological and behavioral aspects of hypnosis, but also studied and wrote about psychic phenomena such as mental suggestion and clairvoyance. One example, and the topic of this paper, was French physician Ambroise August Liébeault (1823-1904), who influenced the Nancy school of hypnosis. Liébeault wrote about mental suggestion, clairvoyance, mediumship, and even so-called poltergeists.

Note on online books and articles about the history of dissociation.

Students of the history of dissociation will be interested in the materials on the subject available in the digital document database Google Book Search. This includes a variety of books and journals covering automatic writing, hypnosis, mediumship, multiple personality, trance, somnambulism, and other topics. Among the authors represented in the database are: Eugène Azam, Alfred Binet, James Braid, Jean-Martin Charcot, Pierre Janet, Frederic W.

Anaplastic large cell neuroblastoma.

Anaplastic large cell neuroblastomas (ALCNB) are a subset of undifferentiated neuroblastomas with marked pleomorphic and anaplastic features that render them diagnostically challenging. We reviewed the records of all patients diagnosed with ALCNB at Children's Healthcare of Atlanta (Egleston Children's Hospital) for their clinical, biologic, and pathologic characteristics and their treatment outcomes. From 1998 to 2006, 7 patients were diagnosed with ALCNB.

Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells.

Background: Tissue factor (TF) is a transmembrane protein that acts as a receptor for activated coagulation factor VII (FVIIa), initiating the coagulation cascade. Recent studies demonstrate that expression of tumor-derived TF also mediates intracellular signaling relevant to tumor growth and apoptosis. Our present study investigates the possible mechanism by which the interaction between TF and FVIIa regulates chemotherapy resistance in neuroblastoma cell lines.

Expression of inhibitor-of-apoptosis protein (IAP) livin by neuroblastoma cells: correlation with prognostic factors and outcome.

Livin is a recently identified member of the Inhibitor-of-Apoptosis protein (IAP) family of antiapoptosis proteins, and expression has been reported in melanoma and some types of carcinoma. We evaluated livin expression in paraffin-embedded tumor tissue from 68 patients with neuroblastoma (NB) and 7 NB cell lines by immunoperoxidase using an anti-livin monoclonal antibody. Eighteen (26.

Autoimmune lymphoproliferative syndrome: a cause of chronic splenomegaly, lymphadenopathy, and cytopenias in children-report on diagnosis and management of five patients.

Autoimmune lymphoproliferative syndrome (ALPS) usually manifests in early childhood with splenomegaly, lymphadenopathy, and cytopenias. In most patients, it results from mutations in genes that regulate lymphocyte apoptosis via the Fas pathway. Here, we report five children with ALPS.