Publications by authors named "Carlos Ruiz-Zamarreno"

Machine learning (ML) and deep learning (DL) have achieved great success in different tasks. These include computer vision, image segmentation, natural language processing, predicting classification, evaluating time series, and predicting values based on a series of variables. As artificial intelligence progresses, new techniques are being applied to areas like optical spectroscopy and its uses in specific fields, such as the agrifood industry.

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The use of planar waveguides has recently shown great success in the field of optical sensors based on the Lossy Mode Resonance (LMR) phenomenon. The properties of Graphene Oxide (GO) have been widely exploited in various sectors of science and technology, with promising results for gas sensing applications. This work combines both, the LMR-based sensing technology on planar waveguides and the use of a GO thin film as a sensitive coating, to monitor ethanol, water, and acetone.

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Pollution in cities induces harmful effects on human health, which continuously increases the global demand of gas sensors for air quality control and monitoring. In the same manner, the industrial sector requests new gas sensors for their productive processes. Moreover, the association between exhaled gases and a wide range of diseases or health conditions opens the door for new diagnostic applications.

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A comprehensive review of optical biosensors for the detection of biomarkers associated with rheumatoid arthritis (RA) is presented here, including microRNAs (miRNAs), C-reactive protein (CRP), rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA), interleukin-6 (IL-6) and histidine, which are biomarkers that enable RA detection and/or monitoring. An overview of the different optical biosensors (based on fluorescence, plasmon resonances, interferometry, surface-enhanced Raman spectroscopy (SERS) among other optical techniques) used to detect these biomarkers is given, describing their performance and main characteristics (limit of detection (LOD) and dynamic range), as well as the connection between the respective biomarker and rheumatoid arthritis. It has been observed that the relationship between the corresponding biomarker and rheumatoid arthritis tends to be obviated most of the time when explaining the mechanism of the optical biosensor, which forces the researcher to look for further information about the biomarker.

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Lossy mode resonance based sensors have been extensively studied in recent years. The versatility of the lossy mode resonance phenomenon has led to the development of sensors based on different configurations that make use of a wide range of materials. The coating material is one of the key elements in the performance of a refractometer.

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The measurement of chemical and biomedical parameters can take advantage of the features exclusively offered by optical fibre: passive nature, electromagnetic immunity and chemical stability are some of the most relevant ones. The small dimensions of the fibre generally require that the sensing material be loaded into a supporting matrix whose morphology is adjusted at a nanometric scale. Thanks to the advances in nanotechnology new deposition methods have been developed: they allow reagents from different chemical nature to be embedded into films with a thickness always below a few microns that also show a relevant aspect ratio to ensure a high transduction interface.

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In this work a novel antibacterial surface composed of an organic-inorganic hybrid matrix of tetraorthosilicate and a polyelectrolyte is presented. A precursor solution of tetraethoxysilane (TEOS) and poly(acrylic acid sodium salt) (PAA) was prepared and subsequently thin films were fabricated by the dip-coating technique using glass slides as substrates. This hybrid matrix coating is further loaded with silver nanoparticles using an in situ synthesis route.

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