Publications by authors named "Carlos R Martinez Sanchez"

Coronary artery aneurysms are a relatively infrequent finding with an incidence of 1% to 2% per year. Its cause can be atherosclerosis, congenital or due to other causes less common. Its initial manifestation can be myocardial infarction and sudden death as a result of rupture or distal embolization.

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Objective: This study was designed to explore the presence of a prothrombotic state, fibrinolytic dysfunction and inflammation in impaired glucose tolerance subjects, by evaluating serum markers of thrombosis, fibrinolysis and inflammation.

Methods: In 48 consecutive adults, 25 patients with impaired glucose tolerance (nine men and 16 women, 50.0 ± 9.

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The evolution of reperfusion treatment has permitted an improvement in the prognosis and survival of patients with Acute myocardial infarction with ST elevation. The benefit of thrombolitic therapy was demonstrated clearly starting with the first trials of ISIS 2. It was also demonstrated this benefit is greater when the thrombolitic is combined with aspirin.

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Article Synopsis
  • Cardiogenic shock (CHC) linked to acute myocardial infarction has traditionally had a very high mortality rate of 98%, which has improved to 53% with advanced reperfusion methods.
  • Proper clinical stratification based on factors like age, infarction location, heart rate, and blood pressure can enhance treatment strategies.
  • In patients with CHC, those with cardiac power below 1.0 after reperfusion showed significantly higher mortality rates, highlighting the importance of measuring myocardial work parameters.
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Hemodynamic monitoring has been used extensively during the last decades for risk stratification and guiding treatment of patients with cardiovascular destabilization, especially in the scenario of acute heart failure and cardiac shock. Every cardiac pump has its own maximum performance, which denotes its pumping capability. The heart is a muscular mechanical pump with an ability to generate both flow (cardiac output) and pressure.

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The use of heparins in acute coronary syndromes has been established as antithrombine indication. In acute myocardial infarction, it is considered an adjunct therapy to reperfusion strategies. In patients with angina, this antithrombine therapy experts a synergic effect with antiplatelet drugs, which also have an antithrombine effect.

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