In vivo long-term kinetics of radiolabeled n,n-dimethyltryptamine and tryptamine.

Unlabelled: N,N-dimethyltryptamine (DMT), a strong psychodysleptic drug, has been found in higher plants, shamanic hallucinogenic beverages, and the urine of schizophrenic patients. The aim of this work was to gain better knowledge on the relationship between this drug and hallucinogenic processes by studying DMT behavior in comparison with tryptamine.

Methods: (131)I-labeled DMT and tryptamine were injected into rabbits.