Publications by authors named "Carlos Mestres"

Clinical cases referring to the EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ aim to assist physicians in selecting the best management strategies for individual patients with a given condition. These expert opinions consider the impact on patient outcomes as well as the risk-benefit ratio of different diagnostic or therapeutic methods. These cases serve as a vital tool to aid physicians in making decisions in their daily practice.

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Introduction: Avoiding patient-prosthesis mismatch (PPM) in patients with small aortic annulus (SAA) during aortic valve replacement (AVR) is still a challenging surgical problem. Among surgical options available, aortic root enlargement (ARE) and stentless valve implantation (SVI) are the two most commonly used strategies. This systematic review will be conducted searching for superiority evidence based on comparative studies between these two options.

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Infective endocarditis frequently spreads beyond the valve tissue, especially in the aortic location. Invasive endocarditis may lead to abscess formation or fistula, with substantial tissue loss. Here, the case of a 31-year-old male patient with destructive aortic and pulmonary valve endocarditis and a subaortic mural defect who underwent patch closure of the ventricular septal defect and aortic and pulmonary root replacement and right coronary artery bypass graft is presented.

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Article Synopsis
  • The study compares infective endocarditis (IE) outcomes in patients after surgical aortic valve replacement (SAVR) versus transcatheter aortic valve replacement (TAVR), aiming to identify differences in clinical presentation, microbiological profiles, management, and outcomes.
  • Data was gathered from two international registries, focusing on patients with IE affecting aortic valve prostheses, and included a matched comparison of TAVR and SAVR patients.
  • The findings revealed that patients with surgical bioprostheses had higher rates of complications but similar one-year mortality rates compared to those with TAVR, indicating important differences in infection characteristics and treatment but comparable long-term outcomes.
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  • The safety of exercise for patients with abdominal aortic aneurysms (AAA) is debated due to concerns about the risk of rupture from increased blood pressure during physical activity.
  • This review involves experts from various medical fields who argue that patients should not avoid rigorous exercise and that the fear of rupture is often overstated.
  • By examining the positive effects of exercise and providing tailored safety recommendations, the authors suggest that the benefits of exercise and cardiopulmonary testing exceed the short-term risks related to AAA rupture.
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Introduction: This study was conducted to evaluate the efficacy of postoperative computed tomography (CT) measurements of aortic lumen volumes in predicting aortic-related complications following acute type A aortic dissection (ATAAD) repair.

Methods: We conducted a single-institution retrospective aortic volumetric analysis of patients after ascending aorta replacement performed during 2001-2015. The volumetric measurements of total lumen (total-L), true lumen (TL), false lumen (FL), as well as the TL:FL ratio from the first and second postoperative computer angiograms were obtained.

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Article Synopsis
  • The 2023 Duke-ISCVID IE Criteria update new diagnostic methods and imaging techniques for infective endocarditis, reflecting advancements in microbiology and epidemiology since the original guidelines were published in 1994 and modified in 2000.* -
  • Key changes include new tests for detecting specific bacteria, the introduction of intraoperative inspection as a major criterion, and an expanded list of microorganisms considered typical for IE, especially with certain heart implants.* -
  • Additionally, the updated criteria simplify blood culture requirements and emphasize the need for ongoing updates to these guidelines, proposing that they be maintained as a "Living Document" for continued relevance.*
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  • Homograft heart valves are often better for fixing heart problems in young women, athletes, and patients with active infections.
  • There is a shortage of donated tissues for these valves, so a new program is being started to help collect more tissue donations.
  • Between 2020 and 2022, doctors at the hospital collected several heart and lung parts for transplant, but some were discarded due to issues like contamination or damage.
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Background: Teamwork across medical specialties improves patient outcomes. However, it also places an additional strain on team leaders, who must mediate between the medical specialties while at the same time belonging to one of them. We examine whether a cross-training incorporating communication and leadership skills can enhance multispecialty teamwork in Heart Teams and enable Heart Team leaders.

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  • Heart transplantation (HT) can be a last resort for patients with severe infective endocarditis (IE) and significant heart issues, as shown in a study involving 20 patients across several countries from 1991 to 2021.
  • The study found that the average age of these patients was 50, with a mix of native and prosthetic valve infections primarily affecting aortic and mitral valves; patients experienced major complications like heart failure and abscesses.
  • Despite a 35% mortality rate, particularly in the first month post-transplant, most patients who survived the hospital stay did well after 35.5 months of follow-up, indicating that HT can be a viable option for select individuals with persistent IE.
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Infective endocarditis (IE) is a rare but serious complication following transcatheter aortic valve replacement (TAVR). Despite substantial improvements in the TAVR procedure (less invasive) and its expansion to younger and healthier patients, the incidence of IE after TAVR remains stable, with incidence rates similar to those reported after surgical aortic valve replacement. Although IE after TAVR is recognized as a subtype of prosthetic valve endocarditis, this condition represents a particularly challenging scenario given its unique clinical and microbiological profile, the high incidence of IE-related complications, the uncertain role of cardiac surgery, and the dismal prognosis in most patients with TAVR-IE.

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turns 30 in 2023. A historical review since it was first published in March 1993 is presented.

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Background: Studies investigating cardiac implantable electronic device infective endocarditis (CIED-IE) epidemiological changes and prognosis over long periods of time are lacking.

Methods: Retrospective single cardiovascular surgery center cohort study of definite CIED-IE episodes between 1981-2020. A comparative analysis of two periods (1981-2000 vs 2001-2020) was conducted to analyze changes in epidemiology and outcome over time.

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In patients with infective endocarditis and neurological complications, the optimal timing for cardiac surgery is unclear due to the varied risk of clinical deterioration when early surgery is performed. The aim of this review is to summarize the best evidence on the optimal timing for cardiac surgery in the presence of each type of neurological complication. An English literature search was carried out from June 2018 through July 2022.

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Introduction: There is a lack of information about cardiac surgery training and professional practice in Latin American (LATAM) countries. This study is the first comparative analysis of cardiac surgical training and professional practice across LATAM and provides the fundamentals for future academic projects of the Latin American Association of Cardiac and Endovascular Surgery (LACES).

Methods: International survey-based comparative analysis of the training and professional practice of cardiac surgeons across LATAM.

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