Publications by authors named "Carlos Martinez Macho"
Article Synopsis
- Deep brain stimulation (DBS) is a potential treatment for psychiatric patients with severe, treatment-resistant symptoms, but its effectiveness has varied and is still in an experimental stage due to lack of objective diagnostic criteria.
- This overview reviews the existing literature on different biomarkers that could enhance the application of DBS in psychosurgery, including clinical, omic, neuroimaging, electrophysiological, and neurobiochemical types.
- A deeper understanding of these biomarkers could lead to more objective and effective uses of DBS in psychiatry, making treatments more tailored to individual patients.
Background: Glioblastomas are among the most malignant tumors which, despite aggressive treatment, currently have an abysmal prognosis. These lesions are known to cause local and systemic perturbations in the coagulation system, leading to neoangiogenesis and a high risk of venous thromboembolism. Indeed, there have been multiple proposals of the coagulation system being a possible target for future treatment of these patients.
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