Publications by authors named "Carlos M Orantes Navarro"

In El Salvador, chronic kidney disease had reached epidemic propor-tions towards the end of this century's first decade. In 2011-2012, the Ministry of Health reported it was the leading cause of hospital deaths in men, the fifth in women, and the third overall in adult hospital fa-talities. Farming was the most common occupation among men in dialysis (50.

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Article Synopsis
  • - In El Salvador, a chronic kidney disease (CKD) known as CKDnt is significantly impacting farmers, becoming epidemic and causing tens of thousands of deaths, with studies identifying its prevalence and possible causes.
  • - Research involving over 7,000 participants found that CKD rates among adults in agricultural communities were as high as 18%, with 51.9% of cases being CKDnt, and noted high levels of kidney damage markers in those affected.
  • - The potential causes of CKDnt appear to be complex, potentially linked to factors like exposure to agrochemicals, heat stress, and dehydration, leading to a diagnosis of chronic tubulointerstitial nephropathy in biopsies.
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INTRODUCTION Chronic kidney disease has reached epidemic levels in several Central American countries since the early years of this century. In El Salvador, it is the second cause of death in men, the fifth in persons over 18 years old and the third cause of hospital deaths in the adult population. Its features, especially those of a subtype unassociated with traditional risk factors such as diabetes and high blood pressure, are only partially understood.

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Over the past 20 years, there has been an increase in chronic interstitial nephritis in agricultural communities (CINAC) not associated with traditional risk factors. This disease has become an important public health problem and is observed in several countries in Central America and Asia. CINAC predominantly affects young male farmers between the third and fifth decades of life with women, children, and adolescents less often affected.

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Introduction: In El Salvador end-stage renal disease (ESRD) was the first cause of hospital mortality overall, the first cause of hospital deaths in men, and the fifth cause of hospital mortality in women in 2013. In agricultural communities, chronic kidney disease (CKD) occurs predominantly in male agricultural workers, but it also affects women to a lesser degree, even those who are not involved in agricultural work. Internationally, most epidemiological CKD studies emphasize men and no epidemiological studies focused exclusively on women.

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