Photosymbiosis shaped animal genome architecture and gene evolution as revealed in giant clams.

Symbioses are major drivers of organismal diversification and phenotypic innovation. However, how long-term symbioses shape whole genome evolution in metazoans is still underexplored. Here, we use a giant clam (Tridacna maxima) genome to demonstrate how symbiosis has left complex signatures in an animal's genome.

FGD-Gypsum Waste to Capture CO and to Recycle in Building Materials: Optimal Reaction Yield and Preliminary Mechanical Properties.

The use of waste to capture CO has been on the rise, to reduce costs and to improve the environmental footprint. Here, a flue gas desulfurization (FGD) gypsum waste is proposed, which allows us to obtain a CaCO-based solid, which should be recycled. The CO capture stage has primarily been carried out via the direct carbonation method or at high temperature.

Study of a Fire-Resistant Plate Containing Fly Ashes Generated from Municipal Waste Incinerator: Fire and Mechanical Characteristics and Environmental Life Cycle Assessment.

The recycling of fly ash from municipal solid waste incineration is currently a global issue. This work intends to examine the viability of a novel recycling alternative for fly ashes as a component of fire-resistant plates. To lessen the quantity of heavy metal leaching, the fly ash was utilized after being washed using a water/fly ash ratio of 2 for one hour.

Development of Mortars That Use Recycled Aggregates from a Sodium Silicate Process and the Influence of Graphene Oxide as a Nano-Addition.

This research analyses how different cement mortars behave in terms of their physical and mechanical properties. Several components were necessary to make seven mixes of mortars, such as Portland cement, standard sand, and solid waste from a factory of sodium silicate, in addition to graphene oxide. Furthermore, graphene oxide (GO) was selected to reduce the micropores and increase the nanopores in the cement mortar.

Exceptional population genomic homogeneity in the black brittle star Ophiocomina nigra (Ophiuroidea, Echinodermata) along the Atlantic-Mediterranean coast.

The Atlantic-Mediterranean marine transition is characterised by strong oceanographic barriers and steep environmental gradients that generally result in connectivity breaks between populations from both basins and may lead to local adaptation. Here, we performed a population genomic study of the black brittle star, Ophiocomina nigra, covering most of its distribution range along the Atlantic-Mediterranean region. Interestingly, O.

Genomic signatures suggesting adaptation to ocean acidification in a coral holobiont from volcanic CO seeps.

Ocean acidification, caused by anthropogenic CO emissions, is predicted to have major consequences for reef-building corals, jeopardizing the scaffolding of the most biodiverse marine habitats. However, whether corals can adapt to ocean acidification and how remains unclear. We addressed these questions by re-examining transcriptome and genome data of Acropora millepora coral holobionts from volcanic CO seeps with end-of-century pH levels.

Use of adjuvant ISA VG 71 to produce neutralizing egg yolk antibodies against bothropic venom.

The use of egg yolk antibodies-IgY technology-represents an alternative to the production of mammalian immunoglobulins and has several advantages regarding animal welfare and lower costs of production. The use of adjuvants to achieve the hyperimmunization of laying hens plays a key role in the success of the production of high levels of the antibodies. In the present work, two different adjuvant systems (Freund's adjuvants and Montanide ISA 71 VG) were compared to produce IgY anti-Bothrops alternatus.

In vitro Inhibitory Activity of IgY Antibodies Against Salmonella Ser. Newport Isolated from Horses.

Equine salmonellosis is caused by several Salmonella serotypes, including Salmonella Newport, which cause enterocolitis and diarrhea. Treatment usually includes the administration of antibiotics. However, since multidrug-resistant Salmonella is commonly detected, alternative options to control the pathogen are needed.

In vivo neutralization of bee venom lethality by IgY antibodies.

Bee venom is a complex mixture of molecules, among which melittin and phospholipase A (PLA) are the toxic components involved in envenoming accidents with multiple honeybee stings. Traditionally, the treatment of envenomings has been based on the administration of specific antibodies to neutralize the deleterious effects of toxins. An alternative to mammalian polyclonal antibodies is the use of egg yolk immunoglobulins (IgY) due to their advantages regarding animal welfare and lower costs of production as compared to the conventional production methods.

On the way to specificity - Microbiome reflects sponge genetic cluster primarily in highly structured populations.

Most animals, including sponges (Porifera), have species-specific microbiomes. Which genetic or environmental factors play major roles structuring the microbial community at the intraspecific level in sponges is, however, largely unknown. In this study, we tested whether geographic location or genetic structure of conspecific sponges influences their microbial assembly.

Epidemiology, Outcomes, and Associated Factors of Coronavirus Disease 2019 (COVID-19) Reverse Transcriptase Polymerase Chain Reaction-Confirmed Cases in the San Pedro Sula Metropolitan Area, Honduras.

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused substantial morbidity and mortality worldwide. Few reports exist in Latin America, a current epicenter of transmission. Here, we aim to describe the epidemiology and outcomes associated with coronavirus disease 2019 (COVID-19) in Honduras.

Sustainable management of spent fluid catalytic cracking catalyst from a circular economy approach.

For sustainable growth, an economic model must tend toward a circular system, especially in the field of waste management. This work focuses on the valorization of spent fluid catalytic cracking catalyst from oil refineries, which generate 400,000 metric tons of spent catalyst per year worldwide, most of which is sent to landfills. A new alternative to landfilling is proposed for this waste, based on the combination of acid leaching for the recovery of lanthanum, a valuable rare earth, and the reuse of the leached solid residue as a cement substitute.

IgY-technology (egg yolk antibodies) in human medicine: A review of patents and clinical trials.

IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products.

Population substructure and signals of divergent adaptive selection despite admixture in the sponge Dendrilla antarctica from shallow waters surrounding the Antarctic Peninsula.

Antarctic shallow-water invertebrates are exceptional candidates to study population genetics and evolution, because of their peculiar evolutionary history and adaptation to extreme habitats that expand and retreat with the ice sheets. Among them, sponges are one of the major components, yet population connectivity of none of their many Antarctic species has been studied. To investigate gene flow, local adaptation and resilience to near-future changes caused by global warming, we sequenced 62 individuals of the sponge Dendrilla antarctica along the Western Antarctic Peninsula (WAP) and the South Shetlands (spanning ~900 km).

IgY-based antivenom against Bothrops alternatus: Production and neutralization efficacy.

Antivenom for the treatment of bothropic snakebite is a priority for public health institutions from Latin America. An alternative to the conventional antivenom production is based on the use of egg yolk antibodies - IgY-technology - by immunizing laying hens. In this study, we produced, characterized and assessed the efficacy of IgY-based antivenoms against B.

Synthetic Slag Production Method Based on a Solid Waste Mix Vitrification for the Manufacturing of Slag-Cement.

Herein an innovative process to develop a potential vitreous material with cementing properties is proposed. This process paves a production path through melting industrial waste and subsequently cooling the casting in water. The idea erases the need to reduce the environmental impact of the cement industry in terms of natural resources consumption as well as the re-utilization of abandoned wastes from other industries.

Effects of Clostridium perfringens iota toxin in the small intestine of mice.

Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.

Macroinvertebrate communities from the shallow soft-bottoms of Deception Island (Southern Ocean): A paradise for opportunists.

Deception Island (South Shetland Islands) is an atypical spot in its Antarctic context, being a still active volcano with a submerged caldera. Although the sea-floor of its enclosed bay, Port Foster, has been extensively studied from 40 m down, little is known about the macrozoobenthic composition of its shallower areas. The aim of this study was to characterize the so far unexplored soft-bottom marine macroinvertebrate communities living within the first few meters depth in Port Foster.

Use of co-combustion bottom ash to design an acoustic absorbing material for highway noise barriers.

The present study aims to determine and evaluate the applicability of a new product consisting of coal bottom ash mixed with Portland cement in the application of highway noise barriers. In order to effectively recycle the bottom ash, the influence of the grain particle size of bottom ash, the thickness of the panel and the combination of different layers with various particle sizes have been studied, as well as some environmental properties including leachability (EN-12457-4, NEN-7345) and radioactivity tests. Based on the obtained results, the acoustic properties of the final composite material were similar or even better than those found in porous concrete used for the same application.

Recycled blocks with improved sound and fire insulation containing construction and demolition waste.

The environmental problem posed by construction and demolition waste (C&D waste) is derived not only from the high volume produced, but also from its treatment and disposal. Treatment plants receive C&D waste which is then transformed into a recycled mixed aggregate. The byproduct is mainly used for low-value-added applications such as land escape restoration, despite the high quality of the aggregate.

High fire resistance in blocks containing coal combustion fly ashes and bottom ash.

Fire resistance recycled blocks, containing fly ash and bottom ash from coal combustion power plants with a high fire resistance, are studied in this paper by testing different compositions using Portland cement type II, sand, coarse aggregate and fly ash (up to 50% of total weight) and bottom ash (up to 30% of total weight). The fire resistance, physical-chemical (density, pH, humidity, and water absorption capacity), mechanical (compressive and flexural strength), and leaching properties are measured on blocks made with different proportions of fly ash and bottom ash. The standard fire resistance test is reproduced on 28cm-high, 18cm-wide and 3cm-thick units, and is measured as the time needed to reach a temperature of 180°C on the non-exposed surface of the blocks for the different compositions.

A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth.

Several TLR agonists are effective in tumor immunotherapy, but their early innate mechanisms of action, particularly those of TLR2 agonists, are unclear. Mast cells are abundant surrounding solid tumors where they are often protumorigenic and enhance tumor angiogenesis. However, antitumor roles for mast cells have also been documented.

Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine.

The role of CB2 cannabinoid receptors in the behavioral and neurochemical changes induced by intracaudate administration of 6-hydroxydopamine (6-OHDA) was evaluated. 6-OHDA (12 μg/4 μL) or its vehicle was injected in the caudate-putamen (CPu) of mice overexpressing the CB2 cannabinoid receptor (CB2xP) and wild type (WT) mice. Motor impairment, emotional behavior, and cognitive alterations were evaluated.

Neuronal activity of the red nucleus in Parkinson's disease.

Precise placement of the electrodes for stimulation of the subthalamic nucleus (STN) in Parkinson's disease (PD) is crucial for the therapeutic benefit. As a result of the mistargeting and misplacement of the electrodes during surgery in 2 patients with PD, we have characterized the neuronal firing in the red nucleus (RN) and observed the effects of stimulation of this nucleus. Although the neuronal firing (mean +/- SD) of the RN (34 +/- 4.