Publications by authors named "Carlos Henrique Pereira"
Oral mucositis management with photobiomodulation, Bidens pilosa L. (Asteraceae) and Curcuma longa L. (Zingiberaceae), the FITOPROT herbal medicine, and its influence on inflammatory cytokine levels: a randomized clinical trial.
Support Care Cancer
September 2024
Article Synopsis
- - The study investigated the effectiveness of a mucoadhesive formula (FITOPROT) combined with photobiomodulation (PBM) in reducing oral mucositis (OM) in head and neck cancer patients undergoing radiotherapy.
- - Two groups were formed, one receiving FITOPROT and PBM, and the other only PBM, with assessments made over the course of treatment for OM severity and inflammatory cytokine levels.
- - Results showed no significant difference in OM severity between the two groups, but FITOPROT combined with PBM may help maintain a balance of salivary nitrite and cytokines, potentially lowering severe OM cases.
Effects of a mucoadhesive phytomedicine (Curcuma longa L. and Bidens pilosa L.) on radiotherapy-induced oral mucositis and quality of life of patients undergoing head and neck cancer treatment: randomized clinical trial.
Support Care Cancer
August 2023
Article Synopsis
- - This study aimed to evaluate the effectiveness of a herbal medicine (FITOPROT) combined with photobiomodulation (PBM) therapy and a preventive oral care program (POCP) in treating radiotherapy-induced oral mucositis (ROM) and improving quality of life in head and neck cancer patients.
- - A double-blind clinical trial was conducted with two groups: one received PBM and POCP, while the other received these along with FITOPROT mouthwash, with evaluations at various points during treatment.
- - Results showed no significant differences between the groups in terms of ROM severity or quality of life, indicating that the combination treatment did not provide a notable advantage over PBM and POCP alone.
A prospective study on oral adverse effects in head and neck cancer patients submitted to a preventive oral care protocol.
Support Care Cancer
September 2020
Objective: To evaluate the occurrence and severity of oral complications, number of radiotherapy (RT) interruptions and quality of life (QoL) in a population of head and neck cancer patients receiving a preventive oral care program (POCP) and photobiomodulation therapy (PBMT).
Methods: Prospective cohort of 61 head and neck cancer patients undergoing radiochemotherapy were monitored and submitted to a POCP that included oral hygiene and plaque control, removal of infection foci, dental restorations, periodontal therapy, fluorotherapy, oral hydration, and denture removal at night, combined with daily PBMT. Outcomes included occurrence of adverse effects such as severity of oral mucositis (OM) and oral symptoms (pain, solid and fluid dysphagia, odynophagia, dysgeusia), quality of life impacts, and interruptions of radiotherapy (RT) due to symptoms.
Impaired heart rate variability, Valsalva and 30:15 ratio indexes are associated with reduced submaximal exercise capacity in subjects with diabetes mellitus.
Diabetes Res Clin Pract
September 2019
Aims: To assess cardiac autonomic control and its association with submaximal exercise measured using the 6-minute walk test (6MWT) in subjects with type-2 diabetes mellitus (DM2).
Methods: Cardiac autonomic control was assessed using Ewing's tests and heart rate variability (HRV) in DM2 volunteers (DG, n = 22) and sex-, age- and body mass index-matched non-diabetic controls (CG, n = 22) before, during and after 6MWT.
Results: Before the 6MWT, DG presented lower HRV represented by reduced SDNN [median 28.
Expression of adhesion proteins (E-cadherin and β-catenin) and cell proliferation (Ki-67) at the invasive tumor front in conventional oral squamous cell and basaloid squamous cell carcinomas.
Arch Oral Biol
January 2016
Objective: Investigate, on a comparative basis, the expression of the adhesion molecules E-cadherin (E-cad), β-catenin (β-cat) and the proliferation index (Ki-67) at the invasive tumor front (ITF) in squamous cell carcinoma (SCC) and basaloid squamous cell carcinoma (BSCC).
Material And Methods: Thirty-five SCC and 16 BSCC cases were evaluated by immunohistochemistry. Clinicopathological and survival data were also evaluated and compared.