Adrenal response in children with septic shock.

Objective: To describe the serum cortisol profile and evaluate the adrenal response in children with septic shock, and determine the influence of these factors on the outcome and mortality in this group.

Methods: Between May and November 2003, 22 children with septic shock admitted to two pediatric intensive care units in southern Brazil were followed. Adrenal function was evaluated based on the levels of cortisol measured on the occasion of the diagnosis of septic shock and on the response of serum cortisol 30 min after the administration of intravenous corticotrophin (0.

Glucose level and risk of mortality in pediatric septic shock.

Objective: To study the relationship between serum glucose level and mortality in children with septic shock.

Design: Prospective cohort study.

Setting: Twelve-bed pediatric intensive care unit at the Hospital São Lucas da PUCRS, Porto Alegre, Brazil.

[Adrenal insufficiency in children with septic shock].

Objective: To review the criteria for diagnosing and treating adrenal insufficiency in patients with septic shock.

Source Of Data: Articles published in Brazilian and foreign journals selected through these publicationś websites and Medline, as well as references cited in key articles.

Summary Of The Findings: The literature reports a range betwen 17 and 54% for the finding of adrenal insufficiency in patients with septic shock.