Publications by authors named "Carlos H Alencar"

Scabies is a neglected tropical disease and has been highlighted as a target for control. Sarcoptic mange affects animals, but mange is also considered a zoonosis. We present rapid assessment data on scabies and sarcoptic mange collected from key informants via a web-based questionnaire in Ceará State (1265 data entries).

View Article and Find Full Text PDF

Data on the temporal and spatial evolution of SARS-CoV-2 and local control measures and their effects on morbidity and mortality patterns in rural Brazil are scarce. We analyzed the data from case notification systems, epidemiological investigation reports, and municipal decrees in Itapajé, a small municipality in Ceará State in northeast Brazil. For spatial and spatio-temporal analyses, cases and deaths were mapped.

View Article and Find Full Text PDF

Background: To analyse the temporal trends and spatiotemporal distribution of leprosy relapse in Brazil from 2001 to 2021.

Methods: An ecological study with a temporal trend approach and space-time analysis of leprosy relapse in Brazil was carried out with data from the Notifiable Diseases Information System.

Results: A total of 31 334 patients who experienced leprosy relapse were identified.

View Article and Find Full Text PDF
Article Synopsis
  • Systematic data on tungiasis, a parasitic skin infestation, is limited, prompting a study in Ceará State, Brazil.
  • In a survey of 184 municipalities, 98.3% reported occurrences of tungiasis, with 65.2% indicating current cases and notable severe cases reported.
  • The findings highlight tungiasis as a serious public health issue in the region, necessitating a One Health approach to address the impacts on both humans and animals.
View Article and Find Full Text PDF

Background: Human rabies outbreak transmitted by bats continues to be a relevant public health problem not only in the Amazon region. The disease has affected one of the areas with the greatest poverty in southeastern Brazil, a region inhabited by the Maxakali indigenous people.

Case Presentation: We describe four cases of rabies among indigenous children that occurred in the indigenous village of Pradinho, municipality of Bertópolis, Minas Gerais, Brazil.

View Article and Find Full Text PDF

Objectives: To analyse the flow of cases of visceral leishmaniasis (VL) in the state of Ceará, Brazil, between 2007 and 2021.

Methods: An ecological study was conducted using a spatial approach of newly confirmed cases of VL recorded in the Notifiable Diseases Information System. We identified individuals whose municipality of diagnosis differed from that of their residence.

View Article and Find Full Text PDF
Article Synopsis
  • * Key risk factors for higher mortality include being elderly, black, experiencing jaundice and edema, and not taking prescribed medication, while treatment with pentavalent antimonial significantly reduces the risk of death.
  • * The findings suggest that improving understanding of these risk factors can enhance public health policies and epidemiological surveillance to prevent HVL-related deaths.
View Article and Find Full Text PDF

Objective: We evaluated the impact of direct and indirect medical costs incurred through chikungunya infections in patients treated in Fortaleza, Brazil.

Methods: Cross-sectional study about the cost of illness. The valuation method of medical costs was based on the micro-costing approach (bottom-up).

View Article and Find Full Text PDF
Article Synopsis
  • Human visceral leishmaniasis (HVL) is a significant health concern in Ceará, Brazil, which has high rates of incidence and mortality related to the disease from 2007 to 2021.
  • The study analyzed data from a notifiable diseases information system, revealing peak incidences in 2009 and 2011, along with notable mortality rates concentrated primarily in 2011.
  • Results showed that specific municipalities, particularly in the Northern, Northwestern, and Southern areas of Ceará, faced the highest risks of HVL, indicating a persistent endemic situation throughout the study period.
View Article and Find Full Text PDF

Background: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staff, and to estimate the fraction of asymptomatic individuals by sex and age group.

Methods: We conducted a serological survey of SARS-CoV-2 infections.

View Article and Find Full Text PDF

Rabies transmitted by sylvatic populations has become an increasing concern in Brazil. A total of 113 participants with a history of contact with sylvatic populations were interviewed in 27 municipalities of Ceará State in northeast Brazil. Questionnaires included questions on knowledge, attitudes and practices (KAP) regarding sylvatic rabies.

View Article and Find Full Text PDF

CD44 and CD133 have been considered as cancer stem cell (CSC) markers. Stem cell markers are rarely described in healthy stomach tissues. However, the clinicopathological and prognostic value of CD44 and CD133 in gastric cancer remains controversial.

View Article and Find Full Text PDF

This study aimed to identify the seroprevalence of chikungunya and its associated factors in the city of Quixadá, Ceará, Brazil. We also aimed to identify the spatial distribution patterns of positive cases. A cross-sectional survey was conducted with a questionnaire about clinical symptoms, socioeconomic and demographic factors, and a 10 ml blood sample was collected and analysed by ELISA.

View Article and Find Full Text PDF

Introduction: Rabies is considered one of the most relevant public health problems owing to its high fatality rate and the high number of deaths worldwide.

Methods: We included patients with human rabies who attended a reference hospital in the state of Ceará during 1976-2019.

Results: Data were available for 63 out of 171 (36.

View Article and Find Full Text PDF

In Brazil, the SARS-CoV-2 vaccination program has so far prioritized people over 75 years of age. By the end of March 2021, in Ceará State, a total of 313,328 elderly people had received at least one dose of vaccine (45% Oxford-AstraZeneca/Fiocruz and 55% CoronaVac-Sinovac/Butantan), and 159,970 had received two doses (83% CoronaVac-Sinovac/Butantan and 17% Oxford-AstraZeneca/Fiocruz). After a single dose, there was already a significant reduction in COVID 19-related deaths (protection ratio: 19.

View Article and Find Full Text PDF

Visceral leishmaniasis (VL) is considered as an important tropical disease because it rapidly spreads across a wide geographical area. This study aimed to analyse the temporal and spatial patterns of incidence, mortality and case fatality rates due to human VL in Ceará, Brazil, from 2007 to 2018. This is an ecological study involving time series and spatial analyses, and data were obtained from human VL notifications.

View Article and Find Full Text PDF

Objective: To describe cases of human rabies in Ceará State, Brazil between 1970 and 2019.

Methods: This was a descriptive study using secondary data from the Ceará State Department of Health and the state reference hospital.

Results: Of 171 cases, 75.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on leprosy relapse cases in Ceará from 2001 to 2018, analyzing their trends and prevalence.
  • A total of 1,777 relapse cases were identified, with higher rates among men, illiterate individuals, those of mixed race, and those with specific types of leprosy or visible disabilities.
  • The data indicated a rising trend in leprosy relapse over the study period, highlighting the ongoing challenges in managing the disease in vulnerable populations.
View Article and Find Full Text PDF

Introduction: The state of Ceará (Brazilian Northeast) has a high incidence of dengue. Therefore, we aimed to characterize the temporal patterns and spatial distribution of dengue cases in Ceará during 2001-2019.

Methods: A spatiotemporal ecological study was performed with secondary data.

View Article and Find Full Text PDF

Objective: To analyze the temporal trend and describe the spatial distribution of Visceral Leishmaniasis (VL) in Fortaleza from 2007 to 2017.

Methods: This was an ecological study using segmented temporal regression and thematic mapping.

Results: Between 2007-2017, 1,660 new cases and 97 deaths were confirmed.

View Article and Find Full Text PDF

Background: The State of Ceará, in Northeastern Brazil, suffers from a triple burden of arboviruses (dengue, Zika and chikungunya). We measured the seroprevalence of chikungunya, dengue and Zika and its associated factors in the population of Juazeiro do Norte, Southern Ceará State, Brazil.

Methods: A cross-sectional study of analytical and spatial analysis was performed to estimate the seroprevalence of dengue, Zika and chikungunya, in the year 2018.

View Article and Find Full Text PDF

Objective: To analyze the spatial pattern of AIDS mortality and social factors associated with its occurrence.

Methods: An ecological study that considered 955 AIDS deaths of residents in Piauí, reported in the Mortality Information System (MIS) from 2007 to 2015. Non-spatial and spatial regression models were used to identify social determinants of AIDS mortality, with a significance of 5%.

View Article and Find Full Text PDF
Article Synopsis
  • Visceral leishmaniasis, a deadly disease caused by the Leishmania parasite and primarily transmitted by sandflies, is endemic in Ceara State, Brazil, where dogs serve as the main reservoir.
  • The study analyzed human visceral leishmaniasis (HVL) cases in Ceara from 2003 to 2017, revealing it mainly affects urban males, particularly children under five and young adults aged 30-49.
  • Findings show a concerning trend of increasing incidence and mortality rates, along with a geographic expansion of the disease throughout the region.
View Article and Find Full Text PDF