Comparison of Whole-Body Dosimetry Measurements in I Therapy Using Ceiling-Mounted Geiger-Müller Detectors and γ-Camera Scans: An Agreement Analysis.

In I therapies internal dosimetry is crucial for determining the mean absorbed dose to organs at risk, particularly the bone marrow, which has a dose constraint of 2 Gy. Traditionally, multicompartmental models have been used for bone marrow dosimetry, necessitating whole-body absorbed-dose assessments. However, noninvasive techniques, such as γ-camera scans or ceiling-mounted Geiger-Müller (GM) counters, can estimate the aforementioned.

Regulation of nuclear medicine services: Perception of the problems and challenges in Colombia for the approach to cancer.

Introduction: Colombia has modified the nuclear medicine norms that impact the administration of radioactive iodine therapy in the treatment of thyroid cancer. Objective: To identify the areas of agreement regarding the issue, as well as the current and emergent requirements associated with the normative for the operation of nuclear medicine services that have an impact on the care of patients with thyroid cancer in Colombia. Materials and methods: We conducted a two-round Delphi study for each expert, clinical, and regulatory group.

Diagnostic Performance and Clinical Impact of Ga-PSMA-11 PET/CT Imaging in Early Relapsed Prostate Cancer After Radical Therapy: A Prospective Multicenter Study (IAEA-PSMA Study).

Biochemical recurrence (BCR) is a clinical challenge in prostate cancer (PCa) patients, as recurrence localization guides subsequent therapies. The use of PET with prostate-specific membrane antigen (PSMA) provides better accuracy than conventional imaging practice. This prospective, multicenter, international study was performed to evaluate the diagnostic performance and clinical impact of PSMA PET/CT for evaluating BCR in PCa patients in a worldwide scenario.

Rectal Neuroendocrine Tumor With Inferior Vena Cava Tumor Thrombosis Diagnosed With 68Ga-DOTANOC PET/CT.

A 69-year-old man with a history of back pain, urinary obstruction, and deep vein thrombosis of both lower extremities 4 years earlier was diagnosed with rectal neuroendocrine tumor, grade 2, Ki-67 index 3%. Ga-DOTANOC PET/CT images showed a left pelvic mass extended to the lumen of the inferior vena cava with a high affinity for somatostatin receptor. A tubular focus of radiotracer accumulation after the course of inferior vena cava with filling defect was suggestive of tumor thrombus.

Uptake pattern of [68Ga]Ga-DOTA-NOC in tissues: implications for inflammatory diseases.

Background: [68Ga]Ga-DOTA-NOC binds to somatostatin receptor (SSTR) subtypes 2 and 5, also expressed on lymphocytes and macrophages, but no information is available about uptake in tissues that might be affected by a chronic inflammatory process. Our aim was to obtain normal reference values for: [68Ga]Ga-DOTA-NOC uptake in tissues prone to chronic inflammation.

Methods: Retrospective study in 81 patients who performed the scan for a suspicion of neuroendocrine tumor (NET).

Impulse oscillometry reference values and bronchodilator response in three- to five-year old children living at high altitude.

Introduction: Impulse oscillometry (IOS) is used to measure airway impedance. It is an effective tool for diagnosing and treating respiratory diseases, and it has the advantage that it does not require forced respiratory maneuvers. IOS reference values are required for each population group.

Triple differential cross sections for electron-impact ionization of methane at intermediate energy.

We report an experimental and theoretical investigation of electron-impact single ionization of the highest occupied molecular orbital 1t and the next highest occupied molecular orbital 2a states of CH at an incident electron energy of 250 eV. Triple differential cross sections measured in two different laboratories were compared with results calculated within the molecular 3-body distorted wave and generalized Sturmian function theoretical models. For ionization of the 1t state, the binary peak was observed to have a single maximum near the momentum transfer direction that evolved into a double peak for increasing projectile scattering angles, as has been seen for ionization of atomic p-states.

Prolactin and Estradiol Profile in a Cohort of Colombian Women with Systemic Lupus Erythematosus.

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with multiorgan involvement and wide variability in presentation and course. Although it can appear at any age, women of childbearing age are primarily affected. This has led to the proposal of a hormonal role in the development of SLE.

Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts.

Objectives: Explicit reporting of absolute measures is important to ensure treatment effects are correctly interpreted. We examined the extent to which authors report absolute effects for patient-important outcomes in abstracts of systematic review (SR).

Study Design And Setting: We searched OVID MEDLINE and Cochrane Database of Systematic Reviews to identify eligible SRs published in the year 2010.

Systematic reviews experience major limitations in reporting absolute effects.

Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain how authors of systematic reviews (SRs) absolute effect estimates are reported in. We therefore undertook a systematic survey to identify and describe the reporting and methods for calculating absolute effect estimates in SRs.

Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.

Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias.

Methods: We searched MEDLINE and the Cochrane Database of Systematic Reviews for systematic reviews of randomised trials published in 2010, and reporting a meta-analysis of a dichotomous outcome. We randomly selected 98 Cochrane and 104 non-Cochrane systematic reviews.

Antifungal prophylaxis following heart transplantation: systematic review.

Patients with heart transplantation have a high incidence of infectious complications, especially fungal infections. The aim of the systematic review was to determine the best pharmacological strategy to prevent fungal infections among patients with heart transplant. We searched the PubMed and Embase databases for studies reporting the effectivenesss of pharmacologic strategies to prevent fungal infections in adult patient with a heart transplant.

A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol.

Background: Clinicians, providers and guideline panels use absolute effects to weigh the advantages and downsides of treatment alternatives. Relative measures have the potential to mislead readers. However, little is known about the reporting of absolute measures in systematic reviews.

Drugs for treating giardiasis.

Background: Giardiasis infection may be asymptomatic, or can cause diarrhoea (sometimes severe), weight loss, malabsorption, and, in children, failure to thrive. It is usually treated with metronidazole given three times daily for five to 10 days.

Objectives: To evaluate the relative effectiveness of alternative antibiotic regimens for treating adults or children with symptomatic giardiasis.

Mercury concentrations in muscle and liver tissue of fish from marshes along the Magdalena River, Colombia.

The present research determined the total mercury concentrations in muscle and liver tissue in fish collected from the Magdalena River watershed. A total of 378 muscle samples and 102 liver samples were included in the analysis. The highest mean mercury level in muscle tissue was found in the noncarnivore, Pimelodus blochii.

[Symptoms of anxiety and depression in adolescents between 10 to 17 year-old attending schools in Chía, Colombia].

Objective: This study was aimed at estimating the prevalence of symptoms of depression and anxiety amongst 10 to 17 year-old adolescents still attending school using the CDI and SCARED questionnaires for early screening in Chía, a town near Bogota, from 2008 to 2010.

Method: This was a cross-sectional study of prevalence.

Results: 37% of the 538 adolescents interviewed had anxiety symptoms, 12.

Inequalities in prescription of hydrochlorothiazide for diabetic hypertensive patients in Colombia.

Objective: Evaluating differences in the suitable prescription of thiazides in hypertense patients, according to affiliation regime.

Materials And Methods: This was an analytical cross-sectional study. The database from a previous study was used regarding two groups of hypertense patients (subsidised regime and contributory regime) who had attended out-patient consultation between 01-09-2007 and 29-02-2008.

Quark structure of the nucleon and angular asymmetry of proton-neutron hard elastic scattering.

We investigate an asymmetry in the angular distribution of hard elastic proton-neutron scattering with respect to the 90 degrees center of mass scattering angle and demonstrate that it's magnitude is related to the helicity-isospin symmetry of the quark wave function of the nucleon. Our estimate of the asymmetry within the quark-interchange model of hard scattering demonstrates that the quark wave function of a nucleon based on the exact SU(6) symmetry predicts an angular asymmetry opposite to that of experimental observations. We found that the quark wave function based on the diquark picture of the nucleon produces a correct asymmetry.

Cost of diagnosis and treatment of syncope in patients admitted to a cardiology unit.

Aims: Despite the large number of hospital admissions due to syncope, information on the in-hospital cost of management of these patients remains incomplete.

Methods And Results: In order to assess such cost, we analysed the clinical histories of the patients suffering from syncope who were admitted to our Unit of Cardiology in 2003. We determined the length of stay (in days) for each inpatient, the number of diagnostic tests performed, and the various therapeutic procedures undertaken.