An International Consensus Survey among Pediatric Surgeons on the Role of Appendectomy in Malrotation.

Introduction: Ladd's procedure, originally described in 1936 for the treatment of malrotation, does not traditionally include appendectomy as a standard step. We conducted a multinational survey to investigate the current consensus on the role of appendectomy in Ladd's procedure.

Methodology: An anonymous online survey was distributed to pediatric surgeons worldwide.

Drugst.One - a plug-and-play solution for online systems medicine and network-based drug repurposing.

In recent decades, the development of new drugs has become increasingly expensive and inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly understood. In response, computational systems and network medicine tools have emerged to identify potential drug repurposing candidates. However, these tools often require complex installation and lack intuitive visual network mining capabilities.

Roux-en-Y partial volvulus in biliary-digestive reconstruction in children.

Various complications occur after a biliary-digestive reconstruction. Volvulus of a segment of the biliodigestive loop has not been described. Two patients who underwent biliodigestive bypass, years later, began with sudden and intense abdominal pain, associated with a volvulus with necrosis of a segment of this biliodigestive loop.

Laparoscopic vs Open Extravesical Ureteral Reimplantation in Pediatric Population: A Single-Center Experience.

Purpose: To evaluate the safety and efficacy of conventional laparoscopic vs open Lich-Gregoir ureteral reimplantation in pediatric vesicoureteral reflux.

Material And Methods: A retrospective study was conducted in a tertiary care hospital. Patients with vesicoureteral reflux who underwent open or laparoscopic Lich-Gregoir ureteral reimplantation from 2013-2020 were included.

Intraoperative Endoscopy as an Adjuvant to Minimally Invasive Surgery in Pediatrics.

Minimally invasive surgery has a different visual and tactile perception compared with conventional surgery, which could lead to complications, especially in complex procedures. In these cases, flexible endoscopy can facilitate and prevent complications in minimally invasive procedures in children. The study aimed to clarify the utility of intraoperative endoscopy as an adjuvant to minimally invasive surgery in children.

Tratamiento laparoscópico de un quiste de colédoco gigante en un paciente pediátrico.

Introducción: Se define como quiste de colédoco gigante aquel con un diámetro ≥ 10 cm. A pesar de que el abordaje laparoscópico ha sido contraindicado, se presenta el caso de un adolescente con un quiste de colédoco gigante resuelto por laparoscopía. Caso clínico: Paciente de sexo masculino de 14 años con un quiste de colédoco gigante tratado con anastomosis hepático-duodenal laparoscópica.

Treatment of chronic pancreatitis by laparoscopic DuVal procedure: report of a pediatric case.

Antecedentes: La pancreatitis es una enfermedad rara. La obstrucción es común y se puede corregir con endoscopia; si fracasa, necesitará cirugía.

Caso ClÍnico: Reportamos un paciente con pancreatitis secundaria a páncreas divisum.

Femoral hernia in children: diagnostic and therapeutic challenge. Case report.

IntroducciÓn: Las hernias femorales son raras en la infancia. El defecto está abajo del ligamento inguinal. La frecuencia de un diagnóstico erróneo es de hasta el 75%.

Learning the Edit Costs of Graph Edit Distance Applied to Ligand-Based Virtual Screening.

Background: Graph edit distance is a methodology used to solve error-tolerant graph matching. This methodology estimates a distance between two graphs by determining the minimum number of modifications required to transform one graph into the other. These modifications, known as edit operations, have an edit cost associated that has to be determined depending on the problem.

Laparoscopic Collis-Nissen approach for shortened esophagus treatment in children.

Background: Short esophagus is a disability to obtain a proper portion of abdominal esophagus, thus a lengthening technique is required. Collis approach is the best option.

Objective: To demonstrate effectiveness of laparoscopic Collis-Nissen approach in children.

Laparoscopic Approach of the Obstruction of the Lower Third of the Esophagus in Children.

To review the diagnostic methodology in pediatric patients with obstruction of the lower third of the esophagus as well as minimally invasive therapeutic options. Retrospective study carried out reviewing records of children with esophageal obstruction diagnostic, from 2000 to 2018. They were divided into Group I stenosis secondary to reflux; Group II achalasia; and Group III embryonic remnants.

Thoracoscopic aortopexy to treat severe tracheomalacia in children. Cases report.

Objective: To present our experience in the treatment of the severe tracheomalacia by thoracoscopic approach, as well as its diagnostic methodology, surgical technique, post-operatory evolution and complications.

Clinical Cases: From 2016 to 2017, three patients, 3, 9 and 12 months old, were treated. They showed multiple near sudden death events and had an absolute dependence to assisted ventilation.

Acute gallbladder volvulus: laparoscopic treatment in an infant.

Introduction: Gallbladder volvulus is a rare and difficult to diagnose pediatric entity, its delayed treatment leads to complications. A 9 months old male case solved by laparoscopy is reported.

Case Report: Twelve hours of development with irritability, vomiting and fever.

Ligand-Based Virtual Screening Using Graph Edit Distance as Molecular Similarity Measure.

Extended reduced graphs provide summary representations of chemical structures using pharmacophore-type node descriptions to encode the relevant molecular properties. Commonly used similarity measures using reduced graphs convert these graphs into 2D vectors like fingerprints, before chemical comparisons are made. This study investigates the effectiveness of a graph-only driven molecular comparison by using extended reduced graphs along with graph edit distance methods for molecular similarity calculation as a tool for ligand-based virtual screening applications, which estimate the bioactivity of a chemical on the basis of the bioactivity of similar compounds.

[Thoracoscopic lobectomy for the treatment of tracheal bronchus. A pediatric case report].

Background: Tracheal bronchus is considered a rare, congenital anomaly, which implies the abnormal origin of a bronchus. When related to repetitive infections the bronchus must be resected, usually via an open procedure.

Objective: The aim of this paper is to present the case of a patient with tracheal bronchus of the upper right lobe who presented with repetitive pneumonias.

[Laparoscopic ureterovesical repair for megaureter treatment].

Background: An alternative treatment for obstructive and refluxing obstructive megaureter with ureterovesical junction maintenance through laparoscopy is proposed.

Material And Methods: The series consists of 8 cases, all of them studied because of prenatal hydronephrosis or febrile urinary tract infection. Seven were diagnosed with obstructive megaureter and one with obstructive refluxing megaureter.

[Management of symptoms associated with spasticity in patients with multiple sclerosis].

Objective: To describe the role of nurses in the management of symptoms related to spasticity in patients with multiple sclerosis (MS).

Method: A descriptive study was developed based on a questionnaire on spasticity in MS patients. The questionnarie was completed through an anonymous tele-voting system at a national meeting with nurses involved in the management of these patients.

[Minimally invasive treatment for traumatic chylopericardium. Paediatric case report].

Background: Chylopericardium is a rare occurrence in children. The most common causes are associated with cardiac surgery, malformations of the lymphatic system, idiopathic reasons, among others.

Objective: The case is presented of a patient with traumatic chylopericardium, the diagnostic methodology, and in particular, its successful resolution by surgical means.

Selective transperitoneal aspiration of a distended bowel with a small-caliber needle during laparoscopic Nissen fundoplication: a prospective randomized controlled trial.

Introduction: Anecdotal reports have demonstrated the feasibility of needle aspiration to deflate a distended bowel, but we do not know of any prospective study that has evaluated this technique. We designed a controlled study to evaluate the use of the selective transperitoneal needle aspiration of a bowel loop (STAB) in infants.

Materials And Methods: Candidates were patients of less than 6 months of age, scheduled for laparoscopic Nissen fundoplication, in whom severe colonic distension was observed.

[Laparoscopic vs opened appendicovesicostomy in pediatric patients].

Background: Appendicovesicostomy is commonly employed to facilitate drainage of urine through the catheter. Due to the tendency to less invasive procedures for the treatment of patients with neurogenic bladder, laparoscopy has been used as an alternative to open surgery, with the immediate advantages of postoperative recovery, shorter postoperative ileus, better cosmetic results, lower postoperative pain and early reintegration into everyday life.

Purpose: Compare the results of laparoscopic procedure with open appendicovesicostomy.

Laparoscopic ureterocystoplasty with Mitrofanoff system.

Purpose: To describe a laparoscopic surgical technique for ureterocystoplasty in pediatric patients with the Mitrofanoff procedure.

Patients And Methods: The procedure was performed in 4 patients (2 females and 2 males), 8-11 years old (average, 9.5 years), with a history of myelomeningocele and secondary neurogenic bladder.

[Laparoscopic resection of a gastric giant cavernous hemangioma in a child].

Background: Gastric hemangioma rarely appears during the pediatric age, with only thirteen cases in the medical literature. Its manifestations are digestive bleeding and intestinal obstruction. The bleeding can be severe and for such reasons it is usually necessary to apply surgical procedures.

Laparoscopic approach for inguinal hernia in children: resection without suture.

Background/purpose: The laparoscopic treatment of inguinal hernia in children presents a higher frequency of relapse when suture technique procedures are used. Here, we present an alternative technique consisting of laparoscopic resection of the hernia sac without suture according to the physiopathology of pediatric inguinal hernia.

Methods: In prospective studies from June 2006 to January 2011, pediatric patients with a diagnosis of inguinal hernia were subjected to surgery as follows: resection of the hernia sac without suture was performed with a 3-port laparoscopic approach.

Treatment of splenic cyst by laparoscopic partial splenectomy: case report.

Background: Congenital splenic cysts are rare. They have a tendency to bleed, to become infected or to rupture and, for these reasons, must be treated. Treatment using splenectomy has the advantage of not presenting recurrence but carries the risk of immunological complications.