Unhealthy habits and comorbidities associated with uncontrolled asthma in young people.

Introduction: Asthma is a chronic inflammatory disease of the lower airways that affects more than 260 million people worldwide and has been related to more than 460,000 deaths a year. It is estimated that in 60% of asthma cases, the symptoms are not adequately controlled. The objective of this study was to determine the association between some comorbidities, habits, and health risk behaviors with uncontrolled asthma in a sample of young people with asthma.

Hospital reconversion in response to the COVID-19 pandemic using simulation and multi-objective genetic algorithms.

With the outbreak of the novel coronavirus SARS-CoV2, many countries have faced problems because of their available hospital capacity. Health systems must be prepared to restructure their facilities and meet the requirements of the pandemic while keeping their services and specialties active. This process, known as hospital reconversion, contributes to minimizing the risk of contagion between hospital staff and patients and optimizing the efficient treatment and disposal of healthcare wastes that represent a risk of nosocomial infection contagion.

[Physical inactivity in young people during home confinement due to COVID-19].

Background: Physical inactivity is a highly prevalent condition in the world and has been associated with increased susceptibility to develop comorbidities and present with severe respiratory distress syndrome due to COVID-19.

Objective: To identify the factors present in the family environment and the personal reasons associated with physical inactivity in young people during confinement at home due to COVID-19.

Material And Methods: A cross-sectional study analyzed data from 1,326 young people, ages 15 - 18.

Low Activation of CD8 T Cells in response to Viral Peptides in Mexican Patients with Severe Dengue.

It is acknowledged that antiviral immune response contributes to dengue immunopathogenesis. To identify immunological markers that distinguish dengue fever (DF) and dengue hemorrhagic fever (DHF), 113 patients with confirmed dengue infection were analyzed at 6 or 7 days after fever onset. Peripheral blood mononuclear cells (PBMC) were isolated, lymphocyte subsets and activation biomarkers were identified by flow cytometry, and differentiation of T helper (Th) lymphocytes was achieved by the relative expression analysis of (Th1), (Th2), (Th17), and (T regulatory) transcription factors quantified by real-time PCR.

[Epidemiology in modern times].

The constant advance of diseases, as well as the continuous socio-demographic change has made medical sciences to dig deep in the field of causal research and prevention. For this, epidemiology, whose main axis is to break paradigms, has undergone a very rapid evolution worldwide. Health challenges are becoming greater, which is why training more specialists in epidemiology is a priority need.

[Factors associated with tobacco use in patients with asthma during the confinement due to COVID-19 in an urban region with high numbers of SARS-CoV-2 infections].

Objective: To determine the prevalence and risk factors associated with tobacco use during the period of confinement in light of the COVID-19 pandemic.

Methods: Through an analytical and cross-sectional study, the data of 2, 372 participants were analyzed. The information was collected through a self-administered questionnaire that was built with the Google Forms tool, which was distributed and applied via email and WhatsApp; the private messaging platform.

[Associations between family history of allergy, exposure to tobacco smoke, active smoking, obesity, and asthma in adolescents].

Objective: The relationships between asthma in adolescents and various environmental and social exposures needs to be clarified. The aim of this study was to determine the association between family history of allergy, passive or active tobacco smoking, obesity, and asthma in adolescents.

Subjects And Methods: A population-based case-control study was carried out.