Epidemiology of environmental factors related to beta-catenin pathway and its impact on the development and progression of colorectal cancer.

Colorectal cancer (CRC) is a complex disease, determined by genetic, environmental and lifestyle-associated risk factors. Genetic (inherited) factors have great influence on its development; however, most cases of CRC are sporadic and gradually develop over several years. The main environmental risk factors are associated with b-catenin signaling pathway, including obesity, lack of physical activity, consumption of red and processed meats, alcoholism, and smoking.

Myostatin Levels and the Risk of Myopenia and Rheumatoid Cachexia in Women with Rheumatoid Arthritis.

Background: Myostatin is a regulator of muscle size. To date, there have been no published studies focusing on the relation between myostin levels and myopenia in rheumatoid arthritis (RA).

Objective: Evaluate the value of serum myostatin as a biomarker of cachexia and low skeletal muscle mass (LSMM) in RA patients, along with whether high serum myostatin is associated to these conditions after adjusting for potential confounders.

Palatopharyngeal vesicular enanthem, early finding of COVID-19.

Early diagnosis of SARS-CoV-2 infection is very important to establish timely treatment. In the present report, through the examination carried out in otorhinolaryngology, we found a pearlescent vesicular enanthema in the upper palate in 954/958 patients with the classic strain and it was not found in patients with the English strain. This finding had not been reported.

New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet.

Hypertension is a major public health problem, affecting more than a quarter of the world's population causing serious cardiovascular problems. In recent years, different polymorphisms have been studied and helped to identify some candidate genes and hereditary syndromes associated with the molecular mechanisms involved in the development of hypertension. Therefore, it is important to identify these molecular mechanisms.

[Self-perception of health status in people retired due to diabetes mellitus complications from Guadalajara, Mexico].

Objective: To evaluate self-perception of health status (APES by its Spanish acronym) of people retired due to complications of diabetes mellitus, and what socio-demographic, family, work and clinical characteristics are associated to these variables.

Materials And Methods: Analytical, cross-sectional study in a universe of 240 pensioners who agreed to participate. The APES was evaluated with the EuroQol-5D questionnaire in Spanish, and socio-demographic, family, work and clinical variables were included.

Educational intervention to improve the competence of Mexican physicians to provide nutritional management for diabetes mellitus type 2.

Objective: To evaluate the effect of a participative educational intervention on the clinical competence of Mexican family physicians regarding the nutritional management of patients with diabetes mellitus Type 2.

Materials And Methods: Quasi-experimental study with a before-and-after control group. Convenience sample included 60 family physicians distributed in two social security primary health care units, randomly selected: 30 in the "A" unit and 30 in the "B" unit.

[Differentiated consumption of macronutrients according to sex and age in higher education students].

Objective: To analyze the intake of macronutrients and its relationship with age and sex in higher education students.

Materials And Methods: A cross-sectional study was carried out with 218 higher education students, aged between 18 and 30 years. A validated and reliable instrument was used to measure macronutrient consumption.

[Mortalidad por enfermedad de Alzheimer en México de 1980 a 2014].

Background: Dementias are rarely considered to be a main cause of death; therefore there are only few studies on Alzheimer's mortality covering long periods.

Objective: To describe mortality from Alzheimer's disease in México for the period from 1980 to 2014.

Method: Cross-sectional study where, with official mortality data in Mexico according to codes 331.

[Social representations of Mexican pregnant teenagers about the puerperal care, lactation, and newborn care].

Background: Puerperal care and feeding of the newborn are guided by entrenched cultural meanings between women, so it is important to know and identify how they are acquired and perpetuated. Regarding this knowledge, the social representations that Mexican pregnant teenagers have about puerperium, lactation and newborn care were studied.

Methods: An interpretative study was made based on principles of the theory of social representations.

Clinical competence of Guatemalan and Mexican physicians for family dysfunction management.

Objective: To evaluate the clinical competence of Mexican and Guatemalan physicians to management the family dysfunction.

Methods: Cross comparative study in four care units first in Guadalajara, Mexico, and four in Guatemala, Guatemala, based on a purposeful sampling, involving 117 and 100 physicians, respectively. Clinical competence evaluated by validated instrument integrated for 187 items.

Effect of an educational intervention on the clinical competence for primary healthcare of rheumatic diseases in Mexican physicians.

Objective: To measure the effect of an educational intervention on clinical competences for diagnosis and treatment of rheumatic diseases in primary healthcare physicians working in the Guadalajara Metropolitan Area, Jalisco, Mexico.

Methodology: Quasi-experimental study conducted in physicians from two primary health care units. The study was carried out in a 40 physicians sample, 21 in Group "A" (intervention) and 19 in Group "B" (control).

[Clinical competences for human viral hepatitis treatment of primary healthcare physicians from the Guatemalan social security system].

Objective: To measure the clinical competence for diagnosis and treatment of human viral hepatitis in primary health care physicians.

Methodology: Cross-sectional study in which a previously validated instrument to measure competences was used, and subsequent comparison between physicians at various primary health care units (PHCT) from the Guatemalan Institute of Social Security (GISS). This information was analyzed using descriptive and non-parametrical statistics.

[Clinical competence measurement in Mexican resident physicians for diagnosis and treatment of Chagas disease].

Objective: Evaluate clinical competence of a mexican resident physicians sample for diagnosis and treatment of Chagas disease.

Material And Methods: Cross-sectional and analytic study in 122 resident physicians of epidemiology, family medicine and internal medicine specialty, assigned to a third level medical unit from Guadalajara, Jalisco, Mexico, taking a sample for convenience. An instrument was designed and validated for to evaluate clinical competence in five dimensions: risk factors identification, clinical data identification, diagnostic test interpretation, diagnostic integration and therapeutic resources utilization; that classified competence level in four strata: random defined, low, medium and high, with 89% of reliability accord to Kunder-Richardson test.

[Effectiveness of interventions for improving drug prescribing in Primary Health Care].

Objective: To determine the effectiveness of interventions for improving drug prescribing in Primary Health Care units.

Design: Systematic review and meta-analysis.

Data Sources: Searches were made in MedLine, ScienceDirect, Springer, SciELO, Dialnet, RedALyC and Imbiomed, in Spanish, English and Portuguese, using keywords "drug prescribing", "intervention studies" and "primary health care", indexed in each data base up to August 2014.

[Mortality due to traffic injuries and its impact on life expectancy: a comparison between Mexico and Spain].

Objective: To determine the impact of mortality due to motor vehicle traffic injuries (MVTI) compared with other causes of death on life expectancy in Mexico and Spain during the three-year periods 2000-2002 and 2010-2012 and the weight of the different age groups in years of life expectancy lost (YLEL) due to this cause.

Methods: Based on official death and population data, abridged life tables in Mexico and Spain were constructed for the three-year periods studied. Temporary life expectancy and YLEL for persons aged 15 to 75 years were calculated by selected causes (MVTI, diabetes mellitus, malignant neoplasms and ischemic heart diseases) and age groups in each three-year period.