A quadratic linear-parabolic model-based EEG classification to detect epileptic seizures.

The two-point central difference is a common algorithm in biological signal processing and is particularly useful in analyzing physiological signals. In this paper, we develop a model-based classification method to detect epileptic seizures that relies on this algorithm to filter electroencephalogram (EEG) signals. The underlying idea was to design an EEG filter that enhances the waveform of epileptic signals.

Bayesian EEG source localization using a structured sparsity prior.

This paper deals with EEG source localization. The aim is to perform spatially coherent focal localization and recover temporal EEG waveforms, which can be useful in certain clinical applications. A new hierarchical Bayesian model is proposed with a multivariate Bernoulli Laplacian structured sparsity prior for brain activity.

[Faciobrachial dystonic seizures. Semiologic diagnosis in limbic encephalitis].

Limbic encephalitis (LE) associated with positive potassium channel complex antibodies often manifests with faciobrachial dystonic seizures (FBDS). We retrospectively analyze two cases, admitted to our video-EEG unit between 2006 and 2014. Both patients were males, aged 66 and 76 years respectively, presenting with brief, but very frequent uni/bilateral dystonic brachial movements, hand posturing and ipsilateral facial grimacing.

Single-dose oral lacosamide in refractory simple partial status epilepticus: case report and review.

Objectives: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic.

Method: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (p.o.

Intracranial video-EEG and surgery for focal atonic seizures.

Atonic seizures are epileptic attacks characterised by a sudden loss or diminution of muscle tone. Structures corresponding to inhibitory cortical areas, such as the primary negative motor area or the supplementary negative motor area, could be responsible. We present findings observed in a patient with atonic seizures due to focal epilepsy, who underwent intracranial video-EEG monitoring and epilepsy surgery, and discuss possible underlying mechanisms.

Creutzfeldt-Jakob disease surveillance in Argentina, 1997-2008.

Background: Epidemiological data on Creutzfeldt-Jakob disease (CJD) from Latin America are limited. We present a comprehensive epidemiological survey on CJD patients in Argentina based on systematic surveillance between 1997 and 2008.

Methods: A CJD Surveillance Referral Center (SRC) was established in Argentina in 1997; previously a Neuropathology Referral Center was used from 1983 to 1996.

Epilepsy surgery in Argentina: long-term results in a comprehensive epilepsy centre.

Rationale: Epilepsy surgery procedures started in Argentina more than 50 years ago. This is the first comprehensive and systematic survey of epilepsy surgery long-term outcome from our country.

Methods: A descriptive cohort study was conducted between 1998 and 2008 for drug-resistant epilepsy surgery with a minimum of 12 months follow-up (n=110).

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy.

It is estimated 20-25% of the epileptic patients fails to achieve good control with the different antiepileptic drugs (AEDs) treatments, developing refractory epilepsy (RE). Discovered first in cancer, the activity of P-glycoprotein (P-gp) and others ABC transporters as multidrug-resistance-associated proteins (MRPs) and breast cancer resistant protein (BCRP) are directly related with the refractoriness. We have observed the overexpression of these all transporters in the brain of patients with RE, and according with other authors, all these data suggests an active drug efflux from brain.

[Mycoplasma pneumoniae meningoencephalitis in a young adult].

Mycoplasma pneumoniae infections have extrapulmonary complications that involve the nervous system. The neurologic manifestations are diverse. Although the prognosis is usually favorable, the patients can undergo severe permanent sequelae.

Oxcarbazepine in pregnancy: clinical experience in Argentina.

The potential teratogenicity of antiepileptic drugs (AEDs) is a major concern for women with epilepsy who are considering pregnancy. Traditional AEDs are associated with an at least twofold risk of fetal malformations compared with the general population. The risk of malformations with newer AEDs is unclear.