Background: Acute hemorrhagic leukoencephalitis (AHLE) or Weston-Hurst syndrome is a rare and severe variant of acute disseminated encephalomyelitis (ADEM). It causes fulminant hemorrhagic demyelination of the central nervous system, and has high mortality and morbidity. Due to the increase in cases and to its high rate of mortality, we decided to make a series of cases and a review of the disease.
View Article and Find Full Text PDFBackground: Motor multifocal neuropathy is an immunemediated neuropathy characterized by progressive and asymmetric weakness of the distal extremities, without sensory symptoms, and an important feature of conduction blocks. The objective of this study is to comprehensively describe the nosological and pathogenic implications of this neurodegenerative disorder, given the unclear diagnosis of MMN and the significant challenges it poses.
Clinical Cases: We present three clinical cases with a chronic clinical presentation, in which neuroconduction studies were performed, revealing the presence of anti-IgM GM1 antibodies, consistent with the diagnosis of motor multifocal neuropathy.