Publications by authors named "Carlos Capitan"
Introduction: Active surveillance (AS) seems to be a cost-effective strategy. However, most publications are based on simulation models of theoretical cohorts, and long-term implications are not usually considered.
Objective: To assess the real cost differences of two cohorts of men with low-risk prostate cancer (PCa) treated with AS or laparoscopic radical prostatectomy (LRP) in a public health system.
Article Synopsis
- The GOLIATH study is a 2-year clinical trial comparing two treatments for benign prostatic obstruction: transurethral resection of the prostate (TURP) and photoselective vaporization using the GreenLight XPS laser, with a focus on maintaining treatment effects seen at the 6-month mark over two years.
- The trial involved 281 patients across 29 centers in Europe and measured outcomes like the International Prostate Symptom Score and other health indicators, aiming to prove that GL-XPS is not inferior to TURP.
- Results showed that GL-XPS maintained similar effectiveness and safety compared to TURP over the two years, with fewer complications and comparable reductions in prostate size and specific antigen levels, though some
Purpose: We present the 1-year results of the GOLIATH prospective randomized controlled trial comparing transurethral resection of the prostate to GreenLight XPS for the treatment of men with nonneurogenic lower urinary tract symptoms due to prostate enlargement. The updated results at 1 year show that transurethral resection of the prostate and GreenLight XPS remain equivalent, and confirm the therapeutic durability of both procedures. We also report 1-year followup data from several functional questionnaires (OABq-SF, ICIQ-SF and IIEF-5) and objective assessments.
View Article and Find Full Text PDFBackground: The comparative outcome with GreenLight (GL) photoselective vaporisation of the prostate and transurethral resection of the prostate (TURP) in men with lower urinary tract symptoms due to benign prostatic obstruction (BPO) has been questioned.
Objective: The primary objective of the GOLIATH study was to evaluate the noninferiority of 180-W GL XPS (XPS) to TURP for International Prostate Symptom Score (IPSS) and maximum flow rate (Qmax) at 6 mo and the proportion of patients who were complication free.
Design, Setting, And Participants: Prospective randomised controlled trial at 29 centres in 9 European countries involving 281 patients with BPO.
Objective: To evaluate the role of the weight of the resected specimen after transurethral resection as a predictive factor for recurrence and progression of non-muscle-invasive bladder tumour (NMIBT).
Patients And Methods: The weight of the resected tumour was measured consecutively in 144 subjects who underwent transurethral resection of bladder tumours at our institution. The median (interquartile range [IQR]) follow-up was 58 (61.
Background: High-level evidence to support the use of photoselective vaporization of the prostate (PVP) is limited.
Objective: Assess the efficacy and safety of GreenLight HPS 120-W laser PVP compared with transurethral resection of the prostate (TURP).
Design, Setting, And Participants: A randomized clinical trial was performed with 50 patients having lower urinary tract symptoms due to benign prostatic hyperplasia in each treatment arm.
Objectives: The objective of this article is to describe the diagnosis of bladder outlet obstruction in women and the treatment of urethral strictures as a cause of it.
Method: A bibliographic review was performed in the Medline (PubMed) data base on articles published on the diagnosis of bladder outlet obstruction in women and the treatment of urethral stricture in the period between 1989-2009.
Results: The prevalence of obstruction in women varies between 2.