[Adherence to international guidelines on early management in severe sepsis and septic shock].

Introduction: Complete adherence to early goal-directed therapy has shown a significant reduction in 28-day mortality rate, whereas partial adherence has not shown beneficial effect.

Objectives: The effect of adherence to 6 hour sepsis bundle treatment was evaluated on patients with severe sepsis and septic shock.

Materials And Methods: A prospective cohort study was conducted during a six-month period.