Publications by authors named "Carlos Alberto Nigro"
Article Synopsis
- The study aimed to create predictive equations for determining therapeutic continuous positive airway pressure (CPAP) based on home titration methods, factoring in the type of mask used.
- A total of 702 adult patients with obstructive sleep apnea were analyzed, and two models (M1 and M2) were developed to estimate CPAP requirements; M1 showed higher accuracy than M2.
- The results indicated that M1 had an error margin of ±3.2 cm HO, allowing 79% of patients to start using CPAP with reasonable accuracy compared to 64% for M2.
Purpose: The aims of this study were to assess the cut-off values for oxygen desaturation index ≥ 3% (ODI3) to confirm obstructive sleep apnea (OSA) in subjects undergoing polysomnography (PSG) and home-based respiratory polygraphy (RP), and to propose an algorithm based on pulse oximetry (PO) for initial management of patients with suspected OSA.
Methods: This was an observational, cross-sectional, retrospective study. ODI3 was used to classify subjects as healthy (no OSA = AHI < 5 or < 15 events/h) or unhealthy (OSA = AHI ≥ 5 or ≥ 15 events/h).
Purpose: To assess the relationship between hypoxemia during polysomnography (PSG) and patient-reported night sweats (NS).
Methods: This retrospective observational study included adult patients who completed a standardized sleep questionnaire and the Epworth Sleepiness Scale (ESS) before PSG.
Results: We included 1397 patients (41% women).
Objective: The objective of the study was to develop a multiparametric oximetry indicator (IMp-SpO2) to diagnose obstructive sleep apnea in adults.
Material And Method: This was an observational, retrospective study of diagnostic accuracy. We included adults who had had a diagnostic polysomnography with few artifacts and a total sleep time of at least 180 min in the sleep laboratory.
Objective: To compare pulse oximetry with manual analysis against all signals of respiratory polygraphy.
Material And Methods: This retrospective study estimated sensitivity (S), specificity (Sp) and positive/negative likelihood ratio (LR+/-) of the oxygen desaturation index (ODI-test) and apnea-hypopnea index (AHI-reference).
Results: 3854 patients (61.
Background And Objective: The usefulness of pulse oximetry for the management of obstructive sleep apnea is controversial. The aim of this study was to assess the accuracy for indication of Continuous Positive Airway Pressure (CPAP) treatment in patients with suspected obstructive sleep apnea (OSA) based on clinical and oximetry data as compared to polysomnography (PSG).
Methods: This multicenter observational study involved seven sleep laboratories.
Objective: To evaluate the performance of clinical criteria (CC) for diagnosis and initiation of empirical treatment with continuous positive airway pressure (CPAP) in patients with suspected obstructive sleep apnea (OSA) compared with the treatment decision based on sleep studies (polysomnography or respiratory polygraphy), guidelines, and experience of participating physicians.
Methods: This was a simulated intention-to-treat study in a retrospective (G1) and prospective (G2) cohort. Four observers (two per group) called CC1 and CC2 reviewed the sleep questionnaires and indicated CPAP if the patients presented snoring, frequent apneas (≥ 3-4/week), body mass index (BMI) > 25 kg/m, sleepiness (Epworth > 11), or tiredness (at least 3-4 times per week) and some comorbidity (hypertension, coronary/cerebrovascular event, diabetes).
Background: It has been reported that the clinical expression of obstructive sleep apnea (OSA) may differ in women and men.
Objective: The objective of this study was to evaluate the influence of gender on reported OSA-related symptoms in a large clinical population of patients.
Methods: The database from the sleep laboratory of a tertiary care center was examined.
Background: There is scarce information about whether the diagnosis of OSA supported only by medical record data can be a useful and reliable tool to initiate a CPAP treatment.
Objectives: The aim of this study is to develop and assess the accuracy of clinical parameters for the diagnosis and prescription of CPAP in patients with suspected OSA.
Methods: Adult patients who underwent polysomnography and completed the Berlin questionnaire, a clinical record, and the Epworth sleepiness scale were included in the study.
Background: Patients under treatment with continuous positive airway pressure (CPAP) may have residual sleep apnea (RSA).
Objective: The main objective of our study was to evaluate a novel auto-CPAP for the diagnosis of RSA.
Methods: All patients referred to the sleep laboratory to undergo CPAP polysomnography were evaluated.
Objective: The aim of the study was to validate the automatic and manual analysis of ApneaLink Ox™ (ALOX) in patients with suspected obstructive sleep apnea (OSA).
Methods: All patients with suspected OSA had a polysomnography (PSG) and an ALOX performed in the sleep laboratory. For automatic analysis, hypopnea was defined as a decrease in airflow ≥30 % of baseline for at least 10 s plus oxygen desaturation ≥3 or 4 %.
Objective. To evaluate the accuracy and reliability of the medical decision based on the results of the hand scoring from a two-channel recording device (ApneaLink) plus clinical data for the prescription of a CPAP assay in patients with suspected OSA. Methods.
View Article and Find Full Text PDFObjective: The aim of this study was to assess the accuracy of oximetry and the clinical parameters for the prescription of continuous positive airway pressure (CPAP) in patients with suspected obstructive sleep apnea syndrome (OSAS).
Methods: All participants (135) performed oximetry (WristOx 3100™) and polysomnography (PSG) simultaneously in the sleep laboratory. The patients completed the Epworth sleepiness scale, the Berlin questionnaire, and a clinical history.
Objective: This study aims to compare the manual correction of the automatic analysis of ApneaLink™ between a skilled observer in the interpretation of sleep studies and a subject trained only in the scoring of ApneaLink™ device.
Methods: Ninety-six subjects performed the ApneaLink™ and polysomnography (PSG) simultaneously in the sleep laboratory. Two blind observers, who were independent from the results of the PSG, performed first the automatic scoring and then the hand correction from the ApneaLink™ device.
Objective: The purpose of this study was to compare the performance of the automated detection versus the manual scoring from the ApneaLink™ device to diagnose obstructive sleep apnoea syndrome (OSAS).
Methods: All participants (96) performed the ApneaLink™ (AL) and polysomnography (PSG) simultaneously in the sleep laboratory. The two recordings were interpreted blindly.
Objective: To evaluate the diagnostic accuracy of the Nonin WristOx 3100 and its software (nVision 5.0) in patients with suspicion of sleep apnea/hypopnea syndrome (SAHS).
Methods: All participants (168) had the oximetry and polysomnography simultaneously.
Background: The objective was to determine the effect of inhaled salbutamol on PEEPi dyn in spontaneously breathing patients with stable severe chronic obstructive pulmonary disease (COPD).
Material/methods: Eleven patients with COPD were studied (mean age: 63 years, average FEV1 0.71 +/- 0.
Background: The aim of this study was to evaluate the relationship between the duration of arousal and the type, duration and minSaO(2) of apneas/hypopneas, and the time of night and sleep stage when they occurred.
Material/methods: We measured the duration of arousals associated with apneas (A) and hypopneas (H) in 10 polysomnographic recording. Arousals were categorized as: 1) Short Electroencephalographic Arousal (SEA: 3-15 s) and 2) Awakenings (>15 s).