Publications by authors named "Carlo Virginio Agostoni"
Article Synopsis
- This study investigates three chromatinopathies (Wiedemann-Steiner, Kleefstra, Coffin-Siris syndromes) known for similar symptoms like intellectual disability and growth issues, to explore their potential metabolic connections.
- Eleven patients participated in the study, where researchers conducted physical exams and assessed resting energy expenditure, finding no significant differences between these conditions and healthy controls.
- The findings highlight the importance of epigenetic factors in growth and neurodevelopment, suggesting that certain clinical features should be monitored in these syndromes, while emphasizing the need for further research into energy metabolism.
Factors behind Antibiotic Therapy: A Survey of Primary Care Pediatricians in Lombardy.
Int J Environ Res Public Health
August 2024
Article Synopsis
- - Antimicrobial resistance (AMR) is a major health concern mainly due to the incorrect use of antibiotics for non-bacterial illnesses, prompting the study of pediatricians' prescription habits in Lombardy.
- - A survey of 253 pediatricians revealed that while many recognize the importance of a national AMR strategy, half view AMR as rare in children, with diagnostic uncertainty being a key factor influencing their antibiotic prescriptions.
- - The study concluded that the challenge in accurately diagnosing infections is the primary factor affecting antibiotic use, overshadowing influences such as parental pressure and legal fears.
Background: The accurate assessment of resting energy expenditure (REE) is essential for personalized nutrition, particularly in critically ill children. Indirect calorimetry (IC) is the gold standard for measuring REE. This methodology is based on the measurement of oxygen consumption (VO) and carbon dioxide production (VCO).
View Article and Find Full Text PDFCeftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children.
View Article and Find Full Text PDFCoronavirus disease 2019 (COVID-19) is caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even if predominantly considered a respiratory pathogen, it could be associated with gastrointestinal involvement, generally in mild forms. Recent reports highlight the association between SARS-CoV-2 and intussusception in infants.
View Article and Find Full Text PDFIntroduction: Acute Rheumatic Fever (ARF) is a multisystemic disease that results from an autoimmune reaction due to group A streptococcal infection. The disease affects predominantly children aged 5 to 15 years and although its incidence in developed Countries declined since the early 1900s, to date there is a paucity of data that confirm this epidemiological trend.
Objective: The study aimed to assess the burden of ARF in term of hospitalization and to describe the characteristics of acute rheumatic fever (ARF) in the paediatric population of Lombardy.