Orbital volume augmentation using expandable hydrogel implants in acquired anophthalmia and phthisis bulbi.

The purpose of this study is to describe our experience using expandable spherical hydrogel implants and injectable hydrogel pellets for orbital volume augmentation in cases of post-enucleation socket syndrome after acquired anophthalmia or phthisis bulbi. We retrospectively reviewed the clinical records of all adult patients who received an expandable hydrogel implant for orbital volume loss following enucleation or phthisis bulbi at the Emory Eye Center between 2004 and January 2007 and the Yale Eye Center between 2009 and 2011. The study included 9 women and 5 men with a mean age of 51.

Bilateral corneal perforations and autoproptosis as self-induced manifestations of ocular Munchausen's syndrome.

Purpose: To report a patient with bilateral corneal perforations and autoproptosis in a case of ocular Munchausen's syndrome.

Design: Case report.

Participant: A 26-year-old white male referred to the oculoplastics service with one month history of decreased vision bilaterally and painful right eye.

Coats-like response in linear en coup de sabre scleroderma.

Purpose: To describe a Coats-like response and central nervous system vasculitis and its successful management in a patient presenting with en coup de sabre scleroderma.

Methods: Retrospective interventional case report. Chart review.

Oculoplastic technique of connecting a glaucoma valve shunt to extraorbital locations in cases of severe glaucoma.

Purpose: To describe a technique for inserting glaucoma shunts to the sinuses or the lacrimal sac as a means of lowering intraocular pressure in patients with refractory glaucoma associated with severe ocular surface disease.

Methods: Nineteen patients with severe ocular surface disease necessitating a keratoprosthesis and with intractable glaucoma underwent placement of a modified Ahmed shunt to direct aqueous in the maxillary or ethmoid sinus or lacrimal sac.

Results: Intraocular pressure is presently well controlled without glaucoma medications in two thirds of patients.

Transcaruncular orbital decompression for management of compressive optic neuropathy in thyroid-related orbitopathy.

This study was conducted to assess the outcome of transcaruncular orbital decompression to treat compressive optic neuropathy in thyroid-related orbitopathy. It involved a retrospective, noncomparative case series of 18 eyes of 10 consecutive patients with documented vision loss secondary to thyroid-related orbitopathy. Bony decompression of the orbital apex was performed via a transcaruncular approach.

Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells.

Purpose: To compare activation of the p42/p44 mitogen-activated protein kinase (MAPK) by cholinergic agonists and epidermal growth factor (EGF) in cultured human and rat goblet cells.

Method: . Conjunctiva was removed from either humans during ocular surgery or male Sprague-Dawley rats and cultured in RPMI medium.

Isolation and characterization of cultured human conjunctival goblet cells.

Purpose: To isolate and characterize goblet cells from normal human conjunctival tissue to determine whether epidermal growth factor (EGF) receptors are present and whether EGF can influence goblet cell proliferation.

Methods: Goblet cells were isolated from explant cultures established from normal conjunctival tissue harvested from patients during periocular surgery. The cells were grown in RPMI culture medium supplemented with 10% fetal bovine serum and characterized using morphology, histochemistry, indirect immunofluorescence microscopy, molecular biology, and biochemistry.

Ptosis after cataract surgery.

An often over-looked complication of routine cataract surgery is post-operative ptosis. This form of ptosis is often transient, although persistent ptosis may require surgical intervention. The causes include eyelid edema and hematoma, anesthesia myotoxicity, and use of a lid speculum or bridle suture.

Transorbital craniotomy through a suprabrow approach: A case series.

Six cases of posterior orbital mass lesions are described in which a suprabrow approach was utilized for transorbital craniotomy. This technique offers several advantages over traditional supraorbital and transcranial approaches to deep orbital tumors. The results were anatomically and cosmetically excellent in all cases.