Role of CuCl PET/CT in Detecting and Staging Muscle-Invasive Bladder Cancer: Comparison with Contrast-Enhanced CT and F-FDG PET/CT.

Molecular imaging of muscle-invasive bladder cancer (MBC) is restricted to its locoregional and distant metastases, since most radiopharmaceuticals have a urinary excretion that limits the visualization of the primary tumor. CuCl a positron-emitting radiotracer with nearly exclusive biliary elimination, could be well suited to exploring urinary tract neoplasms. In this study, we evaluated the feasibility of CuCl-based staging of patients with MBC; furthermore, we compared the diagnostic capability of this method with those of the current gold standards, that is, contrast-enhanced CT (ceCT) and F-FDG PET/CT.

Implantation of AMS 700 LGX penile prosthesis preserves penile length without the need for penile lengthening procedures.

Implantation of an inflatable penile prosthesis (IPP) is a well-established definitive solution for erectile dysfunction when conservative treatments fail. Penile implants may shorten the penis. The AMS 700 LGX IPP is in common use but reports on its mechanical reliability, medium-term postsurgical patient satisfaction, and mean penile length preservation are lacking.

Phosphodiesterase type 5 inhibitor treatment for erectile dysfunction in patients with end-stage renal disease receiving dialysis or after renal transplantation.

Introduction: The phosphodiesterase type 5 (PDE5) inhibitors are generally well tolerated and effective for treating erectile dysfunction (ED), including in patients with significant comorbidity. Because of this benign safety profile, investigators have used PDE5 inhibitors to treat patients with ED and severe renal disease or those who have received renal transplants.

Aim: To assess safety and efficacy of PDE5 inhibitors in patients receiving dialysis or renal transplants.

Chronic urinary retention in men: how we define it, and how does it affect treatment outcome.

What's known on the subject? and What does the study add? Chronic urinary retention (CUR) is a poorly defined entity, as the key element of definition, significant postvoid residual urine volume (PVR), has not a worldwide and moreover evidenced-based definition. There is no agreement on which is the threshold value to define a significant PVR and different society produced guidelines with different thresholds ranging from 300 mL to 1000 mL. Diagnosis is difficult, and management has not been defined yet.

Could plaque excision surgery with sis graft induce a new fibrotic reaction in la Peyronie's disease patients?

Objectives: Peyronie's disease is an acquired disorder of tunica albuginea characterized by the formation of a fibrous plaque which may be associated with pain during erection, penile shortening and/or curvature, difficult vaginal penetration and erectile dysfunction. Severe deformity and/or intractable erectile dysfunction require surgical management. The plaque excision with grafting technique requires the complete excision of the fibrotic tissue and its replacement with an autologous or eterologous graft; among the latter, porcine small intestine submucosa graft is widely used.