Introduction: Domestic violence and abuse (DVA) are prevalent among persons with severe mental illness (SMI), being involved as victim, perpetrator, or both.
Aims: To assess rates of DVA victimization and perpetration in patients with SMI. We also aimed to assess whether DVA victimization was associated with DVA perpetration, and whether this was mediated by dispositional anger in patients with SMI.
Background: Numerous studies have explored the relationship between sleep quality and internalizing symptoms (i.e., depression and anxiety), but there is uncertainty about their directional pathways.
View Article and Find Full Text PDFObesity is recognized as a public health challenge. During the last three decades, the global age-standardized prevalence increased from 8.8% to 18.
View Article and Find Full Text PDFBackground: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) lower ambulatory blood pressure (ABP) in patients with type 2 diabetes mellitus; whether the same holds true in diabetic kidney disease (DKD) is unknown. This information is critical to the knowledge of mechanisms of nephroprotection and safety of this therapy.
Methods: This multicenter prospective study evaluates the changes in ABP after 12 weeks of dapagliflozin 10 mg/day in a cohort of patients with type 2 DKD and glomerular filtration rate (GFR) >25 mL/min/1.
The present study examined longitudinal trajectory classes and correlates of triarchic psychopathy domains (boldness, meanness, and disinhibition) from age 16 to 22, leveraging Multidimensional Personality Questionnaire (MPQ)-based triarchic scales data gathered on a large community sample (s ranging between 483 and 775 across waves) oversampled for parental substance use disorder (SUD). Growth mixture models were conducted to examine longitudinal trajectory classes for each domain, and their associations with environmental covariates (e.g.
View Article and Find Full Text PDFThe assessment of anxiety symptoms in children and adolescents requires a valid and reliable single instrument able to detect various anxiety symptoms early and systematically collect data from other informant such as parents. The present study aimed to test the one-factor structure of the SCAS-P-8 and to examine its psychometric properties and invariance across sex and age in an Italian sample of 769 parents of children and adolescents aged 3-18 years (50.8% females).
View Article and Find Full Text PDFObjective: Research so far has investigated the bivariate relationships between psychopathic traits, romantic attachment, and emotion dysregulation. However, no research thus far has examined these concepts in their interrelatedness. The aim of the present study was therefore to shed light on the possible linking mechanisms among these concepts, examining the mediating role of emotion dysregulation in the psychopathic traits-romantic attachment link.
View Article and Find Full Text PDFConsidering the sparse but rapidly growing literature concerning the relationship between psychopathy and emotion regulation, taking stock of accumulating knowledge in a systematic review and meta-analysis of the existing results is needed. We performed a systematic search (up to May 30, 2024) following PRISMA guidelines of five scientific databases (PsycINFO, PsycARTICLES, MEDLINE, PubMed, Scopus and Web of Science). Also, gray literature was searched.
View Article and Find Full Text PDFIntroduction: Iron deficiency is common in patients with non-dialysis-dependent chronic kidney disease (NDD-CKD). Oral iron supplementation is recommended in these patients, but it is associated with a higher incidence of gastrointestinal adverse reactions. Liposomal iron therapy has been proposed as a new iron formulation, improving iron bioavailability with less side effects; however, few data are available in patients with NDD-CKD.
View Article and Find Full Text PDFNephrology is an ever-evolving field of medicine. The importance of such a discipline is related to the high clinical impact of kidney disease. In fact, abnormalities of kidney function and/or structure are common in the general population, reaching an overall prevalence of about 10%.
View Article and Find Full Text PDFBackground: The Short Dark Tetrad (SD4) is a recently developed instrument for assessing the "dark" personality traits of psychopathy, narcissism, Machiavellianism, and sadism. We aimed to examine the SD4's psychometric properties, adapting it into Spanish and exploring its structure, gender invariance, reliability, concurrent validity, and nomological network.
Method: A sample of 668 adults (Mage = 26.
Objective: Despite accumulating evidence of significant albeit moderate associations between childhood trauma and psychopathy, little is known about the potential moderators of these associations. To advance knowledge in this area, the present study investigated the moderating role of resilience in the childhood trauma-psychopathy link.
Method: A community sample of 521 adult participants from the Netherlands (40.
Clin Kidney J
January 2024
Background: Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are new therapeutic agents for anaemia in chronic kidney disease (CKD). We evaluated by meta-analysis and meta-regression the efficacy and safety of HIF-PHIs in patients with CKD-related anaemia.
Methods: We selected phase 3 randomized clinical trials (RCTs) comparing HIF-PHIs and erythropoiesis-stimulating agents (ESAs) in dialysis and non-dialysis patients.
Background And Objectives: Psychopathic traits - and especially callous affective features - have been linked to altered processing of others' emotional expressions, and to reduced attention to the eyes. Despite the importance of gaze cueing (i.e.
View Article and Find Full Text PDFRationale & Objective: The standard of care (SoC) group of randomized controlled trials (RCTs) is a useful setting to explore the secular trends in kidney disease progression because implementation of best clinical practices is pursued for all patients enrolled in trials. This meta-analysis evaluated the secular trend in the change of glomerular filtration rate (GFR) decline in the SoC arm of RCTs in chronic kidney disease (CKD) published in the last 30 years.
Study Design: Systematic review and meta-analysis of the SoC arms of RCTs analyzed as an observational study.
Trauma-related disorders are debilitating psychiatric conditions that influence people who have directly or indirectly witnessed adversities. Dramatic brain/body transformations and altered person's relationship with self, others, and the world occur when experiencing multiple types of traumas. In turn, these unfortunate modifications may contribute to predisposition to trauma-related vulnerability conditions, such as externalizing (aggression, delinquency, and conduct disorders) problems.
View Article and Find Full Text PDFThe prevalence of recovery of kidney function (RKF) in patients under maintenance dialysis is poorly defined mainly because of different definitions of RKF. Therefore, to gain more insights into the epidemiology of RKF, we performed a systematic review and meta-analysis of studies addressing the prevalence of sustained (at least for 30 days) RKF in patients under maintenance dialysis. Acute kidney injury (AKI) and RKF in the first 90 days of dialysis were the main exclusion criteria.
View Article and Find Full Text PDFIn 2016, a systematic review and a meta-analysis of existing data on the effects of switch from agalsidase beta to alfa in patients with Fabry disease showed that the switch was well tolerated and associated with stable disease progression. However, additional evidence that supports the need for an update of the review on the long-term effects of switching to agalsidase alfa, with a mention on the effects of reswitch to agalsidase beta, has emerged. Relevant papers were identified on PubMed, Cochrane, ISI Web, and Scopus databases from September 2015 to December 2021.
View Article and Find Full Text PDFPsychopathy has traditionally been linked with heightened criminality, but the relationship of psychopathy with increased risk for dangerousness is contested. To address this debated issue, we conducted an umbrella review (PROSPERO CRD42020214761) of all available meta-analyses of psychopathy and indices of 'dangerousness' (e.g.
View Article and Find Full Text PDFChronic kidney disease (CKD) is a complex and multifactorial disease, and one of the most prevalent worldwide. Chronic kidney disease-mineral bone disorders (CKD-MBD) with biochemical and hormonal alterations are part of the complications associated with the progression of CKD. Pathophysiology of CKD-MBD focused on abnormalities in serum levels of several biomarkers (such as FGF-23, klotho, phosphate, calcium, vitamin D, and PTH) which are discussed in this review.
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