Publications by authors named "Carlo Ambrosini"

Background: When the histological examination indicates papillary thyroid carcinoma (PTC), there is no unanimity on the need to proceed with completion thyroidectomy (CT). This study aims to assess the histologic parameters that influenced the decision to perform CT.

Materials And Methods: This study included PTC patients who underwent thyroid lobectomy between 2019 and 2022.

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Background: Parathyroid gland (PG) surgery is often challenging due to the small size and indistinct nature of these glands. The introduction of intraoperative near-infrared autofluorescence (NIRAF) has shown promise in localizing parathyroid tissue. However, the NIRAF features of parathyroid adenomas remain unclear.

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Article Synopsis
  • Researchers created a 3D model of the thyroid gland to study how different substances, like 3-MNT, affect thyroid cells better than flat 2D cultures.
  • They tested the model using special techniques to see how the cells looked and how well they worked, finding that the 3D structure behaved more like real thyroid tissue.
  • The study found that 3MNT changed the activity of a specific thyroid enzyme and affected the production of important proteins, making the 3D model a useful tool for understanding thyroid health.
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Purpose: Assessing vocal cord mobility is crucial for patients undergoing thyroid surgery. We aimed to evaluate the feasibility and efficacy of surgeon-performed transcutaneous laryngeal ultrasound (TLUS) compared to flexible nasolaryngoscopy.

Method: From February 2022 to December 2022, we conducted a prospective observational study on patients scheduled for total thyroidectomy at our Institution.

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Introduction: The COVID-19 pandemic has limited the availability of healthcare resources for non-COVID patients and decreased elective surgeries, including thyroidectomy. Despite the prioritization of surgical procedures, it has been reported that thyroidectomy for thyroid cancer (TCa) was adversely impacted. We assessed the impact of the pandemic on the surgical activities of two high-volume referral centers.

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Obesity is a well-known public health concern in Western World. Accordingly, an elevated number of obese patients undergo thyroidectomy every year. We aim to assess the impact of obesity on intraoperative and postoperative outcomes of patients who undergo thyroidectomy.

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Background: The use of robot-assisted transaxillary thyroidectomy (RATT) has rapidly spread in the last 2 decades, although it is mostly limited to Asian countries.

Method: We retrospectively enroled all patients with histologic diagnoses of thyroid cancer who underwent RATT at the University Hospital of Pisa from May 2012 to September 2020.

Results: The study included 242 patients; 128 (47%) underwent total thyroidectomy and 114 (53%) underwent thyroid lobectomy, among which 28 patients (24.

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Article Synopsis
  • Doctors in Asia often use robots to help with thyroid surgery, but it's still new in Western countries.
  • A study looked at how long it takes for a doctor with no robot experience to get good at this type of surgery in Europe, tracking over 583 patients.
  • It found that the doctor needed to perform 66 surgeries to get better at thyroid lobectomy and 56 surgeries for total thyroidectomy, with some factors helping to make the surgery faster.
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In this paper we describe the current status of sentinel node mapping (SNM) in thyroid tumors and its potential perspectives. SNM in thyroid cancer has been tested since the end of the twentieth century, mainly in papillary thyroid cancer (PTC) and in medullary thyroid cancer (MTC). In PTC, it has been employed to find occult lymph node metastases in the central compartment of the neck as an alternative or indication for prophylactic dissection, by several methods.

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Background: Latarjet surgery and capsuloplasty are both valid alternatives for the treatment of anterior shoulder instability with limited glenoid bone loss, although in literature there is extensive discussion on it. The purpose of this study was to compare the outcomes of these procedures in patients with similar lesions.

Methods: Between January 2000 to October 2020, 59 nonconsecutive patients suffering from anterior shoulder instability were treated, 33 had arthroscopic capsuloplasty (Group 1) and 26 had open Latarjet procedure (Group 2).

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In 2016, the American Thyroid Association published a statement on remote-access thyroid surgery claiming that it should be reserved to patients with thyroid nodule ≤ 3 cm, thyroid lobe < 6 cm and without thyroiditis. We retrospectively enrolled all patients who underwent robotic transaxillary thyroidectomy between February 2012 and March 2022. We compared surgical outcomes between patients who presented a thyroid gland with a nodule ≤ 3 cm, thyroid lobe < 6 cm and without thyroiditis (Group A) and patients without these features (Group B).

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Article Synopsis
  • The case study discusses a rare adrenal neoplasm misidentified as pheochromocytoma but found to be an adrenal cortical tumor upon histological examination.
  • The diagnosis was supported by electron microscopy, which showed neuroendocrine granules alongside lipid droplets in the tumor cells.
  • Following laparoscopic surgery to remove the tumor, the patient's urine levels of metanephrine and normetanephrine returned to normal, highlighting the importance of accurate diagnosis when symptoms and lab results differ from histological findings.
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Background: Near-infrared autofluorescence and indocyanine green fluorescence are 2 recent tools introduced to improve postoperative parathyroid function during thyroid surgery.

Methods: We conducted a randomized prospective study. Patients undergoing total thyroidectomy were randomly assigned either to the fluorescence group, in which near-infrared autofluorescence and indocyanine green fluorescence were used, or to the control group.

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Background: Adrenocortical carcinoma (ACC) is a rare malignant tumor with a poor prognosis. Radical surgical resection with negative margins represents the only opportunity for a potential cure. This review provides a critical assessment of the existing studies regarding the surgical approaches for the treatment of ACC.

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Fewer than 100 cases of amiodarone-induced thyrotoxicosis (AIT) managed surgically have been reported worldwide. This study aims to assess the outcome of thyroidectomy under general anesthesia in a relatively large case series. A retrospective analysis of the clinical records of 53 patients who underwent thyroidectomy for AIT between 1995 and 2019 was conducted.

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The implantation of short femoral stems has significantly increased over the past decade, thanks to their preservation of bone stock, allowing for easier potential revision of components and physiological joint reconstruction. Their main features are metaphyseal fixation and partial retention of the femoral neck which lead to biomechanical advantages and high stability. They also guarantee the preservation of bone stock and insertion through minimally invasive approaches.

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Background: Energy-based devices are surgical devices increasingly utilized for thyroid surgery, owing to a reduction of operative time and surgical related complications. The aim of the study is to evaluate whether the use of energy-based devices could improve the complication rate in pediatric thyroid surgery.

Methods: This is a retrospective observational study.

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Background: Large thyroid masses, particularly if rapidly growing, are often characterized by compression and infiltration of the vital structures of the neck. Therefore, an early and precise diagnosis, not only of malignancy but also of histotype, is mandatory to set up the right therapy. The aim of this study was to evaluate the diagnostic performance of fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in this setting.

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Background: In thyroid surgery, wrong-site surgery (WSS) is considered a rare event and seldom reported in the literature.

Case Presentation: This report presents 5 WSS cases following thyroid surgery in a 20-year period. We stratified the subtypes of WSS in wrong target, wrong side, wrong procedure and wrong patient.

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Objective: Prophylactic central compartment lymph node dissection (pCCND) results in a higher percentage of surgical-related complications. To date, no evidence of the impact of pCCND on the clinical outcome of papillary thyroid carcinoma (PTC) patients with synchronous ipsilateral cervical lymph node metastases has been reported.

Methods: We evaluated all consecutive patients affected by PTC and synchronous ipsilateral cervical, but without evidence of central compartment, lymph node metastases.

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Article Synopsis
  • An 85-year-old woman had a painful thyroid lump, and doctors weren't sure if it was cancer or not.
  • Tests showed she had an infection that made her thyroid swollen, but the results were hard to interpret.
  • Doctors decided to do surgery to remove the problem, which helped her feel much better and showed that it was an infection, not cancer.
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Background: Infections of the spine and hip joint are not common and, as described in literature, they are occasionally linked by a psoas abscess. In patients suffering back pain with history of spondylodiscitis, the spine as primary source of infection for a secondary psoas abscess should always be included in differential diagnosis. A delay in diagnosis of the psoas abscess could lead to septic femoral head necrosis.

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Tibiotalocalcaneal arthrodesis (TTCA) in severe bone deficit represents a complex challenge for expert orthopedic surgeons also. This study aims to illustrate a surgical technique, defined as "ball in basket", that facilitates the fitting of the structural bone graft (femoral head from bone bank) and its placement, in order to fill the bone gap during instrumented arthrodesis. The proposed technique includes the preparation of the recipient bone surfaces with acetabular convex reamers and of concave reamers to shape the bone graft from bone bank.

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Background: Minimally invasive video-assisted thyroidectomy (MIVAT) was first described in 1999 and it has become a widespread technique performed worldwide. Although initially limited to benign thyroid nodules, MIVAT was progressively adopted for all types of thyroid diseases, while remaining within the selection criteria. It is reported that, in selected cases, MIVAT is comparable to standard open thyroidectomy (SOT) in terms of oncologic radicality, time, costs and complications rate, with the advantage of a better cosmetic result and a lower post-operative pain.

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Background: Percutaneous alcoholization with phenol by electrostimulation guidance for the treatment of Morton's neuroma is proposed to determine a permanent chemical neurolysis.

Methods: 115 patients for 125 Morton's neuromas were treated. Ten patients were affected by multiple neuromas.

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