A randomized controlled trial of amoxicillin plus clavulanate compared with cefaclor for treatment of acute otitis media.

We performed a randomized controlled trial of amoxicillin plus clavulanate versus cefaclor for treatment of acute otitis media. Total daily doses given in three divided doses were 40 mg/kg amoxicillin plus 10 mg/kg clavulanate, and 40 mg/kg cefaclor. Pathogens were eradicated from the middle ear exudate after 3 to 6 days of therapy in 35 (97%) of 36 patients given amoxicillin-clavulanate compared with 24 (75%) of 32 given cefaclor (P = 0.

The somatomedin activity in plasma from patients with multiple mechanical injuries: with observations on plasma cortisol.

The somatomedin activity (SMA) was assayed in 247 plasma samples from 30 patients with moderate or severe injuries. The injury severity score (ISS) was assessed for each patient and ranged from 9 to 50. The plasma SMA was reduced or eliminated within 4 days of injury.

Ovulation and reproductive hormones following steroid pretreatment, calf removal and GnRH in postpartum suckled beef cows.

Two experiments were conducted to determine the effect of calf removal, steroid pretreatment and treatment with gonadotropin releasing hormone (GnRH) on subsequent reproductive hormone secretion and ovulation. In the first experiment, GnRH was administered to postpartum beef cows at two levels (100 and 250 microgram) and in two carrier vehicles (saline and carboxymethylcellulose [CMC]). Although peak luteinizing hormone (LH) concentrations were similar for all cows, the interval from treatment to peak LH release and the duration of the LH release was prolonged (P < .

Sound stimulation and its effect on dental sensation threshold.

The success of "auditory analgesia" in dental operations may be a result of distraction, suggestion, or cross-sensory masking, or of a combination of the three. An attempt to separate these influences was made by measuring the change in sensitivity to electrical stimulation of the teeth in typical dental patients upon presentation of loud white noise. No differences in this "tingle" threshold under noise and no-noise conditions were found, either when preliminary instructions were neutral or after implicit or explicit suggestion that the noise would raise the threshold.