Manganese (Mn) is essential for life in plants and animals but can be toxic at high levels, often seen with MnSO in agriculture and mining exposure.*
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Its excessive presence (hypermanganesemia) in mammals leads to neurological issues similar to Parkinson's disease, affecting dopaminergic neural circuits and potentially other health aspects.*
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Research using Drosophila and crustaceans showed that high Mn levels hinder development, survival, and cardiac function, while also blocking certain neural responses and synaptic transmissions.*