Publications by authors named "Carla X Murillo-Jauregui"
Background: The 6-minute walk test is widely used and evaluates the functional capacity to perform sub-maximal exercise, its behavior in healthy young native hight-altitude resident is unknown.
Objective: To describe the behavior of the 6-minute walk test in healthy young native hight-altitude resident.
Material And Methods: Analytical cross-sectional design.
Chronic exposure to altitude has been associated with hypobaric hypoxia in its inhabitants. Two entities have been associated with it, high altitude pulmonary hypertension and chronic mountain sickness. Its physiological and pulmonary circulation characteristics are described, as well as its clinical profile and diagnosis.
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- There is significant variability in pulmonary artery pressure among people living at high altitudes, and the role of a patent foramen ovale (PFO), which is found in about 25% of the general population, may contribute to this variability in those with chronic mountain sickness.
- A study involving healthy high-altitude dwellers and patients with chronic mountain sickness found that the prevalence of PFO (32%) was consistent with low-altitude populations and did not differ significantly between the two groups.
- The presence of a PFO was linked to enlarged right ventricular (RV) size, an increased right-ventricular-to-right-atrial (RV-RA) pressure gradient, and a reduced ability of the RV to change during