Publications by authors named "Carla Simeoni"

Objective: The objective of our study is to evaluate the clinical outcomes and safety of radiofrequency thermal ablation (RFA) for benign thyroid nodules (BTNs) over a 1-year follow-up.

Subjects And Methods: This is a monocentric retrospective study. Forty-eight patients with solid, non-functioning BTNs were treated by RFA using a 17G internally cooled electrode.

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Context: Ultrasound-guided radiofrequency ablation (RFA) of solid thyroid nodules (TNs) is a minimally invasive procedure that may induce a volume reduction of symptomatic solid benign TNs.

Objective: The aim of the study was to evaluate the effectiveness and safety of RFA in debulking benign TNs.

Design And Patients: Eighty-four consecutive patients with symptomatic and cytologically benign solid nodules were randomly assigned to either a single RFA session (group A; n = 42) or follow-up (group B; n = 42) at our center.

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A survey was conducted to evaluate average levels of indoor radon and gamma doses in all educational buildings (506 schools) located in South-East Italy (the Salento peninsula, province of Lecce). In this paper the final findings relating to measurements performed with SSNTD dosemeters in 438 schools (86% of the sample) are reported. The average annual activity concentration of radon in schools located in the province of Lecce is 209 ± 9 Bq/m(3).

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The identification of reliable biomarkers is critical for the assessment of occupational exposure of benzene: S-phenylmercapturic acid (SPMA) and trans,trans-muconic acid (t,t-MA) are the most currently used. t,t-MA is an open-ring metabolite, but it is also a metabolite of the food preservative sorbic acid, while SPMA is formed by conjugation with glutathione, and several studies suggested that the genetic polymorphism of glutathione S-transferases modulates its production. This study compared the ability of these metabolites to assess the benzene exposure in a big group of petrochemical workers.

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