Publications by authors named "Carla Maria Leone"

Introduction: The periodic monitoring of Legionella in hospital water networks allows preventive measures to be taken to avoid the risk of legionellosis to patients and healthcare workers.

Study Design: The aim of the study is to standardize a method for predicting the risk of Legionella contamination in the water supply of a hospital facility, by comparing Machine Learning, conventional and combined models.

Methods: During the period July 2021- October 2022, water sampling for Legionella detection was performed in the rooms of an Italian hospital pavilion (89.

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Background And Aim: Legionnaires' disease is a severe form of pneumonia caused by the inhalation or aspiration of water droplets contaminated with Legionella pneumophila and other Legionella species. These bacteria are commonly found in natural habitats and man-made water systems. Legionnaires' disease is a significant public health problem, especially in healthcare settings where patients may be exposed to contaminated environmental sources.

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Understanding the actual distribution of different Legionella species in water networks would help prevent outbreaks. Culture investigations followed by serological agglutination tests, with poly/monovalent antisera, still represent the gold standard for isolation and identification of Legionella strains. However, also MALDI-TOF and mip-gene sequencing are currently used.

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Article Synopsis
  • The study investigates how atrophic gastritis, especially autoimmune types and advanced cases, affects serum ghrelin levels and body mass index (BMI).
  • It involved 63 patients categorized based on the type of gastritis they had, with tests including endoscopy and multiple gastric biopsies to diagnose and stage the condition.
  • Results indicated that advanced atrophic gastritis was linked to lower ghrelin levels and decreased BMI, while a positive correlation was found between ghrelin levels and BMI in non-obese patients.
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The high prevalence of non-alcoholic fatty liver disease (NAFLD) observed in Western countries is due to the concurrent epidemics of overweight/obesity and associated metabolic complications, both recognized risk factors. A Western dietary pattern has been associated with weight gain and obesity, and more recently with NAFLD. This is a baseline cross-sectional analysis of 136 subjects (79 males) enrolled consecutively in the NUTRIATT (NUTRItion and Ac-TiviTy) study.

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Background: Few studies have examined intestinal motility disorders, which are disabling conditions associated with chronic functional constipation, whose pathogenesis is actually not well-defined.

Aim: To investigate the relationship between serum 25-hydroxyvitamin D levels and functional chronic constipation associated to intestinal motility disorders.

Methods: We performed a prospective case-control study, from May-June to November 2017.

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Introduction: To estimate the effectiveness of two physical activity programs on NAFLD.

Methods: Participants come from a survey conducted in southern Italy. Subjects with moderate or severe NAFLD were invited to participate.

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