Publications by authors named "Carla Jh van der Kallen"

Article Synopsis
  • This study explored the link between autonomic function, indicated by lower heart rate variability (HRV), and beta cell function, assessed during an oral glucose tolerance test (OGTT), using data from 2,007 participants in The Maastricht Study.
  • Researchers found that lower HRV was significantly correlated with worse overall beta cell response, regardless of sex or glucose metabolism status.
  • The findings suggest that autonomic dysfunction could play a role in beta cell dysfunction, potentially leading to issues with glucose metabolism, such as prediabetes and type 2 diabetes.
View Article and Find Full Text PDF

Background And Aims: Arterial remodelling aims at normalising circumferential wall stress (CWS). Greater CWS in the carotid artery has previously been associated with the prevalence and severity of cerebral small vessel disease, a major cause of ageing-related cognitive decline. Here we test the hypothesis that greater carotid CWS is associated with poorer cognitive performance.

View Article and Find Full Text PDF