Publications by authors named "Carla Goncalves Schahin Saa"
Clin Rheumatol
February 2020
Article Synopsis
- This study aimed to evaluate the development of anti-adalimumab antibodies (AAA) in juvenile idiopathic arthritis (JIA) patients undergoing treatment with adalimumab (ADA) over a period of two years.
- It was found that AAA were first observed two months after starting ADA, with a significant increase by the three-month mark; risk factors for developing AAA included being female, having high ESR levels, and using leflunomide, while methotrexate appeared to provide protection.
- The research suggests that early monitoring for AAA is important, as a majority of AAA-positive patients experienced treatment failure and required a switch in medication compared to those without AAA.
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